Adial Pharmaceuticals (ADIL)
Develops precision-oriented therapies for ulcerative colitis and genetically selected alcohol use disorder patients.
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Develops two unapproved precision-oriented drug programs: colon-targeted AT177 for ulcerative colitis and genetically guided AD04 for alcohol use disorder. The business operates with a small internal team and relies on outside providers for development and supply.
Develops two unapproved, precision-oriented drug programs: AT177, an oral colon-targeted prodrug intended for ulcerative colitis, and AD04, a very-low-dose ondansetron treatment paired with a genetic companion test for selected patients with alcohol use disorder. AT177 became the lead program through the acquisition of Azora Therapeutics and remains preclinical; AD04 requires additional pivotal work.
Operates from Virginia with a small internal team, using outside research, manufacturing and clinical-trial providers. Immediate AT177 development is U.S.-oriented, with U.S.-based GMP manufacturing planned, while AD04 development is primarily U.S.-focused and has a proposed, non-definitive European commercialization framework.
Neither program is approved, and the company has no product revenue or internal sales, marketing, or distribution capability. AD04's proposed use depends on both drug approval and an acceptable regulatory path for its companion diagnostic; development and supply depend on CROs, manufacturers and other contractors.
Company facts
Target rangeAs of Sep 22, 2026
Latest analyst notes
| Date | Firm | Action | Prior | Current |
|---|---|---|---|---|
| Aug 3, 2026 | Alliance Global Partners | Initiate | Rating: — | |
| Aug 3, 2026 | Industrial Alliance Securities | Target | Target: — | Target: $11 |
| Jun 15, 2026 | Loop Capital Markets | Target | Target: — | Target: $6 |
| Feb 11, 2026 | UBS | Target | Target: — | Target: $8 |
| Sep 30, 2025 | Maxim Group | Upgrade |
EPSReportedEstimate
RevenueReportedEstimate
Balance sheet, Jun 30, 2026Cash & short-term investments $28.7M · Total debt $0 · Total assets $29.1M · Shareholders' equity $156.0K
- Revenue
- $0
- Operating income
- −$52.0M
- Net income
- −$52.0M
No dividends on record.
| Institutions | 32.90% | 864.0K shares | |
|---|---|---|---|
| 18 holders · as of Jun 30, 2026 | |||
| Insiders | 15.37% | 403.6K shares | |
| 6 holders · as of Jun 16, 2026 | |||
| Strategic holders | 14.79% | 388.3K shares | |
| 1 holder · as of Jul 16, 2026 | |||
| Other | 36.94% | 970.0K shares | |
| remainder | |||
2.63M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing
Two share counts disagree (2.63M in the company's Sep 23, 2026 report, 959.6K elsewhere); stakes use the report.
Top shareholders13F · 13D/G · Form 4
| Holder | Stake | Shares | Date |
|---|---|---|---|
Stonepine Capital Management, LLCInstitution | 27.71% | 727,563 | as of Jun 30, 2026 |
Coastlands Capital LPStrategic10 percent owner | 14.79% | 388,308 | filed Jul 16, 2026 |
Matt DavidsonInsiderdirector, officer: Chief Development Officer | 11.46% | 300,918 | filed Jun 16, 2026 |
Cary J. ClaiborneInsiderdirector, officer: Chief Executive Officer | 1.54% | 40,417 | filed Apr 9, 2026 |
Jane Street Group, LLCInstitution | 1.22% | 32,119 | as of Jun 30, 2026 |
Insider tradesForm 4
| Date | Insider | Role | Shares | Avg price |
|---|---|---|---|---|
| Jul 14, 2026 | Coastlands Capital LP | 10 percent owner | +2,000 | $2.65 |
| Jul 16, 2026 | Coastlands Capital LP | 10 percent owner | +1,233 | $2.75 |
| Jul 9, 2026 | Coastlands Capital LP | 10 percent owner | +10,053 | $2.79 |
| Jul 10, 2026 | Coastlands Capital LP | 10 percent owner | +1,700 | $2.70 |
| Jun 29, 2026 | Coastlands Capital LP | 10 percent owner | +25,000 | $2.60 |
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Compare
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| Adial Pharmaceuticals | $4.02 | −4.29% | $4.0M | — | — | — | — |
| Abivax (ADR) | $93.72 | −4.65% | $7.22B | — | — | — | +3.5% |
| Equillium | $1.72 | −10.88% | $122.0M | — | — | — | — |
| Alkermes | $41.87 | −3.28% | $7.26B | 113.0 | — | 4.4 | +27.0% |
| AbbVie | $264.77 | −0.17% | $468.77B | 74.8 | 17.4 | 7.3 | +10.2% |
| Takeda (ADR) | $18.82 | −0.71% | $60.30B | 52.9 | 59.9 | 2.0 | +4.2% |
| Indivior | $35.89 | −0.84% | $4.52B | 13.0 | 7.9 | 3.4 | +13.6% |
| Median | 63.8 | 17.4 | 3.9 | +10.2% |