Biomea Fusion (BMEA)
Develops oral small-molecule medicines for diabetes and obesity.
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Develops clinical-stage oral medicines centered on icovamenib for diabetes and BMF-650 for obesity. Its business has no approved products or revenue and depends on clinical development and regulatory progress.
Develops oral covalent small-molecule medicines through its FUSION System. The current pipeline centers on icovamenib, a selective covalent menin inhibitor studied in type 1 and type 2 diabetes, and BMF-650, an investigational oral GLP-1 receptor agonist for obesity.
Internal oncology development has ended, while the company seeks partners for those assets and concentrates its resources on metabolic medicine. The strategy moves resource allocation from a prior oncology focus while retaining its small-molecule discovery approach.
With no approved products or revenue, the operating model depends on clinical development and regulatory progress for the remaining programs.
Company facts
Target rangeAs of Sep 22, 2026
Latest analyst notes
No analyst notes in the last 24 months.
EPSReportedEstimate
RevenueReportedEstimate
Balance sheet, Jun 30, 2026Cash & short-term investments $34.8M · Total debt $877.0K · Total assets $36.9M · Shareholders' equity $12.1M
- Revenue
- $0
- Operating income
- −$12.8M
- Net income
- −$8.3M
No dividends on record.
| Institutions | 34.84% | 25.25M shares | |
|---|---|---|---|
| 65 holders · as of Jun 30, 2026 | |||
| Insiders | 2.78% | 2.02M shares | |
| 3 holders · as of Feb 6, 2026 | |||
| Strategic holders | 16.00% | 11.60M shares | |
| 2 holders · as of Feb 17, 2026 | |||
| Other | 46.38% | 33.62M shares | |
| remainder | |||
72.48M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing
Top shareholders13F · 13D/G · Form 4
| Holder | Stake | Shares | Date |
|---|---|---|---|
FMR LLCInstitution | 12.16% | 8.81M | as of Jun 30, 2026 |
CVI Investments, Inc.Strategic | 10.83% | 7.85M | filed Feb 17, 2026 |
Blue Owl Capital Holdings LPInstitution | 6.14% | 4.45M | filed Feb 12, 2026 |
Janus Henderson Group PLCStrategic | 5.17% | 3.75M | filed Dec 8, 2025 |
Vanguard Capital Management LLCInstitution | 3.90% | 2.83M | as of Jun 30, 2026 |
Insider tradesForm 4
| Date | Insider | Role | Shares | Avg price |
|---|---|---|---|---|
| Dec 11, 2025 | Rainer M. Erdtmann | director, officer: See Remarks | +30,000 | $1.43 |
| Dec 2, 2025 | Michael J.M. Hitchcock | director, officer: Interim CEO | +100,000 | $0.9918 |
| Nov 28, 2025 | Rainer M. Erdtmann | director, officer: See Remarks | +40,000 | $1.10 |
| Dec 1, 2025 | Rainer M. Erdtmann | director, officer: See Remarks | +10,000 | $1.05 |
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Compare
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| Biomea Fusion | $1.37 | −19.71% | $122.9M | — | — | — | — |
| Eli Lilly | $1,147.76 | −1.91% | $1.10T | 39.3 | 28.1 | 13.8 | +47.7% |
| Novo Nordisk (ADR) | $38.30 | −2.79% | $174.96B | 9.9 | 15.8 | 3.5 | +1.3% |
| Viking Therapeutics | $39.90 | −2.33% | $4.77B | — | — | — | — |
| Structure Therapeutics (ADR) | $35.03 | −5.11% | $2.12B | — | — | — | — |
| Vertex Pharmaceuticals | $509.92 | −0.98% | $130.71B | 30.0 | 26.5 | 10.4 | +12.5% |
| Sana Biotechnology | $3.11 | −6.61% | $926.7M | — | — | — | — |
| Median | 30.0 | 26.5 | 10.4 | +12.5% |