DNLI · NASDAQ · Biotechnology

Denali Therapeutics (DNLI)

Develops brain-penetrating therapies and commercializes AVLAYAH for Hunter syndrome.

$20.62
vs last close−0.98 (−4.54%)

13F · 13D/G · Form 4

Institutions98.52%157.48M shares
302 holders · as of Jun 30, 2026
Insiders7.04%11.26M shares
13 holders · as of Sep 9, 2026
Adds to105.56%

159.85M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

These groups come from separate filings that can overlap, so they add to 105.56%; nothing is left for Other.

13F · 13D/G · Form 4

HolderStakeSharesDate
T. Rowe Price Investment Management, Inc.Institution
10.12%16.18Mas of Jun 30, 2026
BlackRock, Inc.Institution
8.77%14.03Mas of Jun 30, 2026
Baillie Gifford & CoInstitution
7.48%11.96Mas of Jun 30, 2026
Douglas K. Bratton1Insider10 percent owner
4.91%7.85Mfiled Feb 14, 2022
State Street CorpInstitution
4.41%7.05Mas of Jun 30, 2026
Temasek Holdings (Private) LtdInstitution
4.39%7.01Mas of Jun 30, 2026
Vanguard Portfolio Management LLCInstitution
4.05%6.48Mas of Jun 30, 2026
Vanguard Capital Management LLCInstitution
3.93%6.28Mas of Jun 30, 2026
FMR LLCInstitution
2.84%4.54Mas of Jun 30, 2026
Goldman Sachs Group IncInstitution
2.60%4.16Mas of Jun 30, 2026
Geode Capital Management, LLCInstitution
2.49%3.97Mas of Jun 30, 2026
Holocene Advisors, LPInstitution
2.44%3.91Mas of Jun 30, 2026
Baker Bros. Advisors LPInstitution
2.34%3.73Mas of Jun 30, 2026
UBS Asset Management Americas IncInstitution
1.98%3.16Mas of Jun 30, 2026
Price T Rowe Associates Inc /MD/Institution
1.96%3.14Mas of Jun 30, 2026
UBS Group AGInstitution
1.95%3.12Mas of Jun 30, 2026
AllianceBernstein L.P.Institution
1.87%2.98Mas of Jun 30, 2026
Dimensional Fund Advisors LPInstitution
1.79%2.86Mas of Jun 30, 2026
Norges BankInstitution
1.77%2.82Mas of Jun 30, 2026
Pictet Asset Management Holding SAInstitution
1.75%2.79Mas of Jun 30, 2026
Capital Research Global InvestorsInstitution
1.61%2.57Mas of Jun 30, 2026
Ryan J. WattsInsiderdirector, officer: President and CEO
1.51%2.42Mfiled Aug 14, 2026
Fisher Asset Management, LLCInstitution
1.51%2.41Mas of Jun 30, 2026
Macquarie Management Holdings, Inc.Institution
1.38%2.21Mas of Jun 30, 2026
Casdin Capital, LLCInstitution
1.28%2.05Mas of Jun 30, 2026
  1. Douglas K. Bratton's own ownership statement (13G/A, Feb 14, 2022) reports fewer shares than the transaction reports; the statement is used.

13F, as of Jun 30, 2026

302 holders · 157.48M shares · 57 new positions · 179 increased · 69 reduced · 31 closed

HolderShares% outstandingChg q/qFiled
T. Rowe Price Investment Management, Inc.16.18M10.12%+7.66MAug 14, 2026
BlackRock, Inc.14.03M8.77%+992.0KAug 7, 2026
Baillie Gifford & Co11.96M7.48%−106.2KAug 6, 2026
State Street Corp7.05M4.41%+777.3KAug 7, 2026
Temasek Holdings (Private) Ltd7.01M4.39%0Aug 7, 2026
Vanguard Portfolio Management LLC6.48M4.05%+356.9KAug 13, 2026
Vanguard Capital Management LLC6.28M3.93%+127.8KAug 13, 2026
FMR LLC4.54M2.84%−39.5KAug 13, 2026

13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Baillie Gifford & Co8.60%12.31M13GFeb 12, 2025
BlackRock, Inc.7.20%10.49M13GApr 17, 2025
T. Rowe Price Investment Management, Inc.5.40%8.52M13GMay 15, 2026

Form 4

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Sep 4, 2026
Peter Scott Chinofficer: Chief Medical Officer
Sale1,654$22.29204,538
Sep 2, 2026
Nancy Thornberrydirector
Sale · 2 lots11,439$22.9019,686
Sep 1, 2026
Alexander O. Schuthofficer: COFO and Secretary
Sale2,768$23.44278,995
Aug 11, 2026
Alexander O. Schuthofficer: COFO and Secretary
Sale2,857$25.07281,763
Jan 6, 2026
Alexander O. Schuthofficer: COFO and Secretary
Sale17,218$16.50282,828
Jan 6, 2026
Ryan J. Wattsdirector, officer: President and CEO
Sale35,198$16.50296,833
Dec 11, 2025
Baker Bros. Advisors LPdirector
Purchase · 2 lots2,285,714$0.010025,996,310

House and Senate disclosures

Not reported.