DSGN · NASDAQ · Biotechnology

Design Therapeutics (DSGN)

Develops GeneTAC small molecules that tune disease-causing gene expression.

$12.35
vs last close−0.81 (−6.17%)

13F · 13D/G · Form 4

Institutions≈ 69.57%43.54M shares
141 holders · as of Jun 30, 2026 · largest filers plus last quarter's tail
Insiders28.69%17.95M shares
4 holders · as of Mar 11, 2026
Strategic holders17.86%11.18M shares
3 holders · as of Feb 7, 2025
Adds to116.12%

62.58M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

This quarter's institutional total failed a plausibility check; shown: the largest filers plus last quarter's remainder.

These groups come from separate filings that can overlap, so they add to 116.12%; nothing is left for Other.

13F · 13D/G · Form 4

HolderStakeSharesDate
of 5 PagesInsider
12.25%7.67Mfiled Feb 9, 2022
Simeon George1,2Insiderdirector
10.56%6.61Mfiled Mar 11, 2026
Sr One Capital Management, LPInstitution
10.43%6.53Mas of Jun 30, 2026
Sirenia Capital Management LPInstitution
9.53%5.96Mfiled Aug 14, 2026
Light Irrevocable Trust #1 dated April 22, 20193,4Strategic10 percent owner
6.13%3.83Mfiled Feb 7, 2025
Star Irrevocable Trust #1 dated April 22, 20195,6Strategic10 percent owner
6.13%3.83Mfiled Feb 7, 2025
Arsani WilliamInsiderdirector
5.84%3.66Mfiled Aug 14, 2025
BlackRock, Inc.Strategic
5.61%3.51Mfiled Feb 3, 2023
Logos Global Management LPInstitution
4.79%3.00Mas of Jun 30, 2026
Baker Bros. Advisors LPInstitution
4.28%2.68Mas of Jun 30, 2026
Driehaus Capital Management LLCInstitution
4.25%2.66Mas of Jun 30, 2026
BlackRock, Inc.Institution
4.25%2.66Mas of Jun 30, 2026
Point72 Asset Management, L.P.Institution
3.78%2.37Mas of Jun 30, 2026
Trails Edge Capital Partners, LPInstitution
3.20%2.00Mas of Jun 30, 2026
Frazier Life Sciences Management, L.P.Institution
2.89%1.81Mas of Jun 30, 2026
Vivo Capital, LLCInstitution
2.58%1.61Mas of Jun 30, 2026
Vanguard Capital Management LLCInstitution
2.51%1.57Mas of Jun 30, 2026
Caption Management, LLCInstitution
1.79%1.12Mas of Jun 30, 2026
Almitas Capital LLCInstitution
1.64%1.03Mas of Jun 30, 2026
Geode Capital Management, LLCInstitution
1.53%958,417as of Jun 30, 2026
Sofinnova Investments, Inc.Institution
1.38%865,135as of Jun 30, 2026
FMR LLCInstitution
1.24%776,462as of Jun 30, 2026
Morgan StanleyInstitution
1.22%765,425as of Jun 30, 2026
State Street CorpInstitution
1.18%736,221as of Jun 30, 2026
Woodline Partners LPInstitution
1.12%700,354as of Jun 30, 2026
  1. Simeon George's transaction reports restate only vehicles that traded; the 2026 ownership statement (6.61M) is used instead.
  2. Simeon George reports a block also reported by Sr One Capital Management, LP; it is counted once, under Sr One Capital Management, LP.
  3. Light Irrevocable Trust #1 dated April 22, 2019's transaction reports restate only vehicles that traded; the 2025 ownership statement (3.83M) is used instead.
  4. Light Irrevocable Trust #1 dated April 22, 2019 reports a block also reported by Simeon George; it is counted once, under Simeon George.
  5. Star Irrevocable Trust #1 dated April 22, 2019's transaction reports restate only vehicles that traded; the 2025 ownership statement (3.83M) is used instead.
  6. Star Irrevocable Trust #1 dated April 22, 2019 reports a block also reported by Simeon George; it is counted once, under Simeon George.

13F, as of Jun 30, 2026

141 holders · 43.54M shares · 31 new positions · 92 increased · 32 reduced · 17 closed

HolderShares% outstandingChg q/qFiled
Sr One Capital Management, LP6.53M10.43%0Aug 12, 2026
Logos Global Management LP3.00M4.79%+1.05MAug 14, 2026
Baker Bros. Advisors LP2.68M4.28%+92.5KAug 14, 2026
Driehaus Capital Management LLC2.66M4.25%+916.1KAug 14, 2026
BlackRock, Inc.2.66M4.25%+526.3KAug 7, 2026
Point72 Asset Management, L.P.2.37M3.78%−356.3KAug 14, 2026
Trails Edge Capital Partners, LP2.00M3.20%+1.15MAug 14, 2026
Frazier Life Sciences Management, L.P.1.81M2.89%+1.81MAug 14, 2026

13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Simeon Georgeincl. SR One Capital Partners I, LP, SR One Capital Fund I Aggregator, LP +1 more10.70%6.61M13DMar 11, 2026
Sirenia Capital Management LP9.50%5.96M13GAug 14, 2026
Light Irrevocable Trust #1 dated April 22, 20196.90%3.83M13GFeb 7, 2025
Star Irrevocable Trust #1 dated April 22, 20196.90%3.83M13GFeb 7, 2025
Point72 Asset Management, L.P.5.10%3.20M13GJun 9, 2026

Form 4

Latest trades

No open-market trades in the last 12 months.

House and Senate disclosures

Not reported.