EWTX · NASDAQ · Biotechnology

Edgewise Therapeutics (EWTX)

Developer of sarcomere modulators for hypertrophic cardiomyopathy and heart failure.

$41.26
vs last close−3.25 (−7.31%)

13F · 13D/G · Form 4

Institutions110.32%119.82M shares
238 holders · as of Jun 30, 2026
Insiders0.26%279.6K shares
9 holders · as of Aug 14, 2026
Strategic holders5.45%5.92M shares
1 holder · as of May 15, 2026
Adds to116.03%

108.60M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

These groups come from separate filings that can overlap, so they add to 116.03%; nothing is left for Other.

13F · 13D/G · Form 4

HolderStakeSharesDate
Orbimed Advisors LLCInstitution
14.29%15.52Mas of Jun 30, 2026
Paradigm Biocapital Advisors LPInstitution
9.41%10.22Mas of Jun 30, 2026
Ra Capital Management, L.P.Institution
7.73%8.39Mas of Jun 30, 2026
BlackRock, Inc.Institution
6.08%6.61Mas of Jun 30, 2026
Jupiter Topco LLCInstitution
5.59%6.08Mas of Jun 30, 2026
Janus Henderson Group PLCStrategic
5.45%5.92Mfiled May 15, 2026
FMR LLCInstitution
5.05%5.49Mas of Jun 30, 2026
Novo Holdings A/SInstitution
4.93%5.35Mas of Jun 30, 2026
Driehaus Capital Management LLCInstitution
4.35%4.73Mas of Jun 30, 2026
Perceptive Advisors LLCInstitution
4.03%4.37Mas of Jun 30, 2026
Vanguard Capital Management LLCInstitution
3.55%3.86Mas of Jun 30, 2026
Baker Bros. Advisors LPInstitution
3.41%3.70Mas of Jun 30, 2026
Siren, L.L.C.Institution
2.93%3.18Mas of Jun 30, 2026
Cormorant Asset Management, LPInstitution
2.31%2.51Mas of Jun 30, 2026
Geode Capital Management, LLCInstitution
2.00%2.17Mas of Jun 30, 2026
AllianceBernstein L.P.Institution
1.95%2.12Mas of Jun 30, 2026
Integral Health Asset Management, LLCInstitution
1.84%2.00Mas of Jun 30, 2026
Braidwell LPInstitution
1.84%2.00Mas of Jun 30, 2026
Morgan StanleyInstitution
1.79%1.95Mas of Jun 30, 2026
State Street CorpInstitution
1.68%1.83Mas of Jun 30, 2026
Bioimpact Capital LLCInstitution
1.49%1.62Mas of Jun 30, 2026
Bank of America Corp /DE/Institution
1.43%1.56Mas of Jun 30, 2026
Qube Research & Technologies LtdInstitution
1.15%1.25Mas of Jun 30, 2026
Dimensional Fund Advisors LPInstitution
1.05%1.14Mas of Jun 30, 2026
American Century Companies IncInstitution
1.04%1.13Mas of Jun 30, 2026

13F, as of Jun 30, 2026

238 holders · 119.82M shares · 45 new positions · 128 increased · 75 reduced · 30 closed

HolderShares% outstandingChg q/qFiled
Orbimed Advisors LLC15.52M14.29%0Aug 14, 2026
Paradigm Biocapital Advisors LP10.22M9.41%+2.85MAug 14, 2026
Ra Capital Management, L.P.8.39M7.73%−2.04MAug 14, 2026
BlackRock, Inc.6.61M6.08%+133.3KAug 7, 2026
Jupiter Topco LLC6.08M5.59%+6.08MnewAug 14, 2026
FMR LLC5.49M5.05%+4.47MAug 13, 2026
Novo Holdings A/S5.35M4.93%0Aug 14, 2026
Driehaus Capital Management LLC4.73M4.35%+250.7KAug 14, 2026

13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Orbimed Advisors LLCincl. Orbimed Capital LLC, Orbimed Capital GP Vi LLC +1 more14.50%15.25M13DMay 12, 2025
RA Capital Management, L.P.9.90%10.43M13GNov 14, 2025
Baker Bros. Advisors LP6.90%7.31M13GAug 14, 2025
Paradigm BioCapital Advisors LP6.20%6.54M13GFeb 17, 2026
Janus Henderson Group PLC5.50%5.92M13GMay 15, 2026
BlackRock, Inc.5.50%5.82M13GJul 17, 2025

Form 4

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Aug 12, 2026
Kevin Kochdirector, officer: President and CEO
Sale · 3 lots17,971$43.6852,488
Aug 12, 2026
Behrad Derakhshanofficer: Chief Business Officer
Sale · 4 lots5,100$43.8131,826
Aug 12, 2026
John R. Mooreofficer: General Counsel
Sale · 4 lots5,016$43.8217,697
Aug 12, 2026
Alan J. Russelldirector, officer: Chief Scientific Officer
Sale · 3 lots5,901$43.7331,466
Aug 13, 2026
Joanne M. Donovanofficer: CMO
Sale2,919$43.418,625
Aug 12, 2026
Joanne M. Donovanofficer: CMO
Sale · 4 lots6,522$43.8511,544
Jul 1, 2026
Alan J. Russelldirector, officer: Chief Scientific Officer
Sale · 2 lots200,000$39.4124,555
May 4, 2026
Joanne M. Donovanofficer: CMO
Sale5,230$31.294,367
May 5, 2026
Joanne M. Donovanofficer: CMO
Sale50,000$38.574,367
Apr 1, 2026
Joanne M. Donovanofficer: CMO
Sale28,662$32.319,597

House and Senate disclosures

Not reported.