Structure Therapeutics (ADR) (GPCR)
Develops oral small-molecule medicines for metabolic, cardiovascular, and pulmonary conditions.
$37.20
After-hours close+0.38 (+1.03%)
At close$36.82(+0.03%)
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13F · 13D/G · Form 4
| Institutions | 94.74% | 67.56M ADS | |
|---|---|---|---|
| 202 holders · as of Jun 30, 2026 | |||
| Insiders | 0.54% | 383.6K ADS | |
| 8 holders · as of Sep 22, 2026 | |||
| Strategic holders | 2.08% | 1.48M ADS | |
| 1 holder · as of Nov 14, 2025 | |||
| Other | 2.64% | 1.88M ADS | |
| remainder | |||
71.31M ADS (1 ADS = 3 ordinary shares) as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing
Two share counts disagree (71.31M in the company's Sep 23, 2026 report, 57.57M elsewhere); stakes use the report.
13F, as of Jun 30, 2026
202 holders · 67.56M shares · 30 new positions · 105 increased · 55 reduced · 33 closed
| Holder | Shares | % outstanding | Chg q/q | Filed |
|---|---|---|---|---|
| FMR LLC | 7.81M | 10.95% | −593.1K | Aug 13, 2026 |
| Wellington Management Group LLP | 7.38M | 10.35% | +119.1K | Aug 14, 2026 |
| Avoro Capital Advisors LLC | 6.56M | 9.19% | 0 | Aug 14, 2026 |
| Jupiter Topco LLC | 5.20M | 7.30% | +5.20Mnew | Aug 14, 2026 |
| Deep Track Capital, LP | 4.74M | 6.65% | +460.2K | Aug 14, 2026 |
| BVF Inc/IL | 3.37M | 4.72% | −92.5K | Aug 14, 2026 |
| Morgan Stanley | 2.81M | 3.94% | +501.2K | Aug 13, 2026 |
| Orbimed Advisors LLC | 2.21M | 3.10% | +734.0K | Aug 14, 2026 |
13D/G · 5% or more, as filed
| Holder | % of class | Shares | Form | Filed |
|---|---|---|---|---|
| FMR LLC | 15.00% | 31.11M | 13G | Feb 5, 2026 |
| Wellington Management Group LLP | 10.10% | 21.37M | 13G | Feb 10, 2026 |
| Avoro Capital Advisors LLC | 9.38% | 16.22M | 13G | Nov 14, 2025 |
| Janus Henderson Group PLC | 7.70% | 4.45M | 13G | Nov 14, 2025 |
| Ein #incl. Janus Henderson Group plc | 6.90% | 3.96M | Nov 14, 2024 | |
| Deep Track Capital, LP | 5.95% | 12.34M | 13G | Feb 13, 2026 |
Form 4
Latest trades
| Date | Insider | Type | Shares | Avg price | Owned after |
|---|---|---|---|---|---|
| Sep 21, 2026 | Crespo Blas Collofficer: CHIEF MEDICAL OFFICER | Sale | 4,008 | 1,157 | |
| Sep 1, 2026 | Xichen Linofficer: CHIEF SCIENTIFIC OFFICER | Sale · 3 lots | 5,939 | 0 | |
| Aug 18, 2026 | Xichen Linofficer: CHIEF SCIENTIFIC OFFICER | Sale · 3 lots | 3,939 | 0 | |
| Aug 4, 2026 | Xichen Linofficer: CHIEF SCIENTIFIC OFFICER | Sale · 2 lots | 3,939 | 0 | |
| Jul 22, 2026 | FMR LLC10 percent owner, other: See Remark 1 | Sale · 2 lots | 17,452 | 1,369 | |
| Jul 14, 2026 | Xichen Linofficer: CHIEF SCIENTIFIC OFFICER | Sale · 2 lots | 7,878 | 0 | |
| Jun 25, 2026 | Xichen Linofficer: CHIEF SCIENTIFIC OFFICER | Sale | 7,878 | 0 | |
| Apr 14, 2026 | FMR LLC10 percent owner, other: See Remark 1 | Sale · 2 lots | 17,452 | 2,736 | |
| Jan 15, 2026 | FMR LLC10 percent owner, other: See Remark 1 | Sale · 8 lots | 17,452 | 4,103 | |
| Dec 8, 2025 | FMR LLC10 percent owner, other: See Remark 1 | Sale · 10 lots | 52,356 | 0 |
House and Senate disclosures
Not reported.