IONS · NASDAQ · Biotechnology

Ionis Pharmaceuticals (IONS)

Develops antisense medicines through owned launches and pharmaceutical partnerships.

$45.39
vs last close+0.49 (+1.10%)

13F · 13D/G · Form 4

Institutions≈ 106.48%176.94M shares
556 holders · as of Jun 30, 2026 · largest filers plus last quarter's tail
Insiders0.76%1.27M shares
21 holders · as of Sep 2, 2026
Strategic holders6.92%11.50M shares
1 holder · as of Jun 7, 2018
Adds to114.16%

166.18M company shares as of Sep 22, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

This quarter's institutional total failed a plausibility check; shown: the largest filers plus last quarter's remainder.

These groups come from separate filings that can overlap, so they add to 114.16%; nothing is left for Other.

13F · 13D/G · Form 4

HolderStakeSharesDate
FMR LLCInstitution
14.82%24.63Mas of Jun 30, 2026
Capital World InvestorsInstitution
13.04%21.67Mas of Jun 30, 2026
Biogen Inc.Strategic
6.92%11.50Mfiled Jun 7, 2018
BlackRock, Inc.Institution
6.44%10.70Mas of Jun 30, 2026
Clearbridge Investments, LLCInstitution
4.78%7.95Mfiled Feb 14, 2020
Vanguard Portfolio Management LLCInstitution
4.73%7.86Mas of Jun 30, 2026
Wellington Management Group LLPInstitution
4.60%7.65Mas of Jun 30, 2026
Vanguard Capital Management LLCInstitution
4.34%7.21Mas of Jun 30, 2026
Two Sigma Investments, LPInstitution
3.76%6.25Mas of Jun 30, 2026
Royal Bank of CanadaInstitution
3.72%6.18Mas of Jun 30, 2026
State Street CorpInstitution
2.61%4.33Mas of Jun 30, 2026
T. Rowe Price Investment Management, Inc.Institution
2.38%3.96Mas of Jun 30, 2026
Geode Capital Management, LLCInstitution
2.16%3.58Mas of Jun 30, 2026
Price T Rowe Associates Inc /MD/Institution
1.92%3.18Mas of Jun 30, 2026
JPMorgan Chase & CoInstitution
1.61%2.67Mas of Jun 30, 2026
Artisan Partners Limited PartnershipInstitution
1.59%2.64Mas of Jun 30, 2026
Tweedy, Browne Co LLCInstitution
1.37%2.28Mas of Jun 30, 2026
Deep Track Capital, LPInstitution
1.32%2.20Mas of Jun 30, 2026
Goldman Sachs Group IncInstitution
1.27%2.11Mas of Jun 30, 2026
Baker Bros. Advisors LPInstitution
1.23%2.05Mas of Jun 30, 2026
Deerfield Management Company, L.P. (Series C)Institution
1.19%1.98Mas of Jun 30, 2026
American Century Companies IncInstitution
1.17%1.95Mas of Jun 30, 2026
Franklin Resources IncInstitution
0.98%1.62Mas of Jun 30, 2026
Charles Schwab Investment Management IncInstitution
0.97%1.61Mas of Jun 30, 2026
Sixth Street Partners Management Company, L.P.Institution
0.97%1.61Mas of Jun 30, 2026

13F, as of Jun 30, 2026

556 holders · 176.94M shares · 70 new positions · 278 increased · 153 reduced · 45 closed

HolderShares% outstandingChg q/qFiled
FMR LLC24.63M14.82%+75.3KAug 13, 2026
Capital World Investors21.67M13.04%+482.9KAug 12, 2026
BlackRock, Inc.10.70M6.44%+262.2KAug 7, 2026
Vanguard Portfolio Management LLC7.86M4.73%+50.6KAug 13, 2026
Wellington Management Group LLP7.65M4.60%+1.26MAug 14, 2026
Vanguard Capital Management LLC7.21M4.34%+93.2KAug 13, 2026
Two Sigma Investments, LP6.25M3.76%+394.7KAug 14, 2026
Royal Bank of Canada6.18M3.72%+2.38MAug 14, 2026

13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Capital World Investors12.80%21.19M13GMay 14, 2026
Wellington Group Holdings LLPincl. Wellington Management Company LLP, Wellington Investment Advisors Holdings LLP +1 more5.76%9.07M13GNov 8, 2024
BlackRock, Inc.5.70%9.07M13GApr 17, 2025
Vanguard Capital Management5.05%8.34M13GApr 30, 2026

Form 4

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Jul 30, 2026
Michael R. Haydendirector
Purchase15,000$53.3819,000
Jul 31, 2026
Michael R. Haydendirector
Purchase5,000$51.6024,000
Jul 7, 2026
Holly B. Kordasiewiczofficer: EVP, Chief Development Officer
Sale362$84.3022,096
Jul 7, 2026
Allene M. Diazdirector
Sale10,111$85.423,811
Jul 7, 2026
C. Frank Bennettofficer: EVP, Chief Scientific Officer
Sale · 2 lots20,536$84.9575,018
Jul 1, 2026
Joseph Iii Kleindirector
Sale · 2 lots11,518$79.0411,014
Jun 26, 2026
Eugene Schneiderofficer: EVP, Chf Clinical Develop Ofcr
Sale26,000$81.0577,114
Jun 26, 2026
Patrick R. O'Neilofficer: EVP CLO & General Counsel
Sale3,069$80.0061,470
Jun 26, 2026
Joseph Baroldiofficer: EVP, Chief Business Officer
Sale5,635$80.164,669
Jun 25, 2026
Eric Swayzeofficer: EVP Research
Sale10,602$79.1821,759

House and Senate disclosures

Not reported.