Lisata Therapeutics (LSTA)
Develops certepetide for tumor-penetrating cancer therapy combinations.
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Develops certepetide, an investigational peptide intended to improve delivery of co-administered or tethered therapies into solid tumors. Operates as a single clinical-stage segment, relying on partners and investigator-led trials while potential economics depend on licensing, milestones, royalties, and commercialization.
Develops certepetide, a cyclic peptide being studied with other therapies to help them penetrate solid tumors through the CendR uptake pathway and modify the tumor microenvironment. The pipeline centers on clinical studies in pancreatic and biliary cancers, including investigator-led work in the United States, Australia, New Zealand, Estonia, Latvia, and Lithuania, plus partner-led development in Greater China. The company has no approved products or recurring product sales.
Operates as a single clinical-stage segment, pairing company-sponsored development with investigator trials, territorial licenses, and technology collaborations. Potential economics depend on licensing payments, development and regulatory milestones, royalties, and eventual commercial arrangements; academic sponsors, collaborators, and third parties undertake material clinical and manufacturing work. The portfolio, collaborations, and platform narrative are concentrated on certepetide, while a pending cash tender offer could replace the standalone strategy.
Company facts
No analyst consensus on record.
EPSReportedEstimate
RevenueReportedEstimate
Balance sheet, Jun 30, 2026Cash & short-term investments $10.4M · Total debt $0 · Total assets $11.0M · Shareholders' equity $8.2M
- Revenue
- $0
- Operating income
- −$4.0M
- Net income
- −$2.9M
No dividends on record.
| Institutions | 12.09% | 1.09M shares | |
|---|---|---|---|
| 30 holders · as of Jun 30, 2026 | |||
| Insiders | 15.69% | 1.41M shares | |
| 10 holders · as of Aug 26, 2026 | |||
| Other | 72.22% | 6.51M shares | |
| remainder | |||
9.01M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing
Top shareholders13F · 13D/G · Form 4
| Holder | Stake | Shares | Date |
|---|---|---|---|
Branham Justin EarlInsider | 5.13% | 462,148 | filed Aug 26, 2026 |
David J. MazzoInsiderdirector, officer: President & CEO | 3.46% | 311,890 | filed Jan 13, 2026 |
Vanguard Capital Management LLCInstitution | 3.09% | 278,837 | as of Jun 30, 2026 |
Yakira Capital Management, Inc.Institution | 1.54% | 138,561 | as of Jun 30, 2026 |
CSS LLC/ILInstitution | 1.23% | 110,422 | as of Jun 30, 2026 |
Insider tradesForm 4
No open-market trades in the last 12 months.
- AstraZeneca (ADR)
Biliary-cancer rival through Imfinzi-based chemoimmunotherapy.
- Merck
Biliary-cancer rival through Keytruda-based chemoimmunotherapy.
- Novocure
Pancreatic add-on rival through Tumor Treating Fields.
- Incyte
Cholangiocarcinoma rival through FGFR2-targeted Pemazyre.
Compare
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| Lisata Therapeutics | $1.45 | −2.03% | $13.5M | — | — | 134.8 | −90.0% |
| AstraZeneca (ADR) | $163.75 | −2.74% | $261.12B | 25.3 | 15.4 | 4.3 | +6.4% |
| Merck | $147.55 | −2.23% | $372.73B | 120.7 | 17.1 | 5.6 | +5.1% |
| Novocure | $16.09 | −3.48% | $1.94B | — | — | 2.8 | +15.6% |
| Incyte | $124.70 | −1.76% | $25.73B | 16.2 | 51.6 | 4.4 | +37.7% |
| Median | 25.3 | 17.1 | 4.3 | +11.0% |






