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LSTA · NASDAQ · Biotechnology

Lisata Therapeutics (LSTA)

Develops certepetide for tumor-penetrating cancer therapy combinations.

$1.45
vs last close−0.03 (−2.03%)
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Lisata Therapeutics, Inc.LSTA
Health Care

Develops certepetide, an investigational peptide intended to improve delivery of co-administered or tethered therapies into solid tumors. Operates as a single clinical-stage segment, relying on partners and investigator-led trials while potential economics depend on licensing, milestones, royalties, and commercialization.

Develops certepetide, a cyclic peptide being studied with other therapies to help them penetrate solid tumors through the CendR uptake pathway and modify the tumor microenvironment. The pipeline centers on clinical studies in pancreatic and biliary cancers, including investigator-led work in the United States, Australia, New Zealand, Estonia, Latvia, and Lithuania, plus partner-led development in Greater China. The company has no approved products or recurring product sales.

Operates as a single clinical-stage segment, pairing company-sponsored development with investigator trials, territorial licenses, and technology collaborations. Potential economics depend on licensing payments, development and regulatory milestones, royalties, and eventual commercial arrangements; academic sponsors, collaborators, and third parties undertake material clinical and manufacturing work. The portfolio, collaborations, and platform narrative are concentrated on certepetide, while a pending cash tender offer could replace the standalone strategy.

Company facts

CEODavid J. Mazzo, Ph.D.
ListedSep 15, 2022
ExchangeNASDAQ
HeadquartersBasking Ridge, NJ
CountryUnited States
Employees21
CIK0000320017
ISINUS1280583022

Market cap$13.5M
EPS (ttm)−$1.64
P/E (ttm)−0.9024
ROE-113.8%
P/B1.63
P/S134.77
Dividend yieldDiv yield
Beta0.85vs XLV 0.16

No analyst consensus on record.

Next report
Nov 5, 26
in 43 days
EPS estimate
−$1.13
Revenue estimate
$659.0K
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Feb '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported−$0.55−$0.55−$0.54−$0.49−$0.74−$0.50−$0.32Pending
Estimate−$0.76−$0.53−$0.65−$0.54−$0.51−$1.13
Surprise+27.6%−3.8%+16.9%+9.3%−45.1%

RevenueReportedEstimate

Feb '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported$1.0M$70.0K$100.0KPending
Estimate$100.0K$94.4K$659.0K
Surprise0.0%
Estimate−$1.13
ReportedDue Nov 5, 2026
Estimate$659.0K
ReportedDue Nov 5, 2026
View details

Debt to equity0.00%
Current ratio368.70%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$1.0M$0$70.0K$0$100.0K$0$0
Net income−$4.9M−$4.6M−$4.7M−$4.7M−$4.2M−$3.0M−$4.5M−$2.9M
Net margin0.0%0.0%0.0%

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$5.3M−$4.9M−$5.8M−$4.9M−$4.4M−$3.1M−$4.9M−$4.0M
YoY growthLoss narrowedLoss narrowedLoss narrowedLoss narrowedLoss narrowedLoss narrowedLoss narrowedLoss narrowed

Balance sheet, Jun 30, 2026Cash & short-term investments $10.4M · Total debt $0 · Total assets $11.0M · Shareholders' equity $8.2M

Revenue
$0
Operating income
−$4.0M
Net income
−$2.9M
View details

No dividends on record.

Institutions12.09%1.09M shares
30 holders · as of Jun 30, 2026
Insiders15.69%1.41M shares
10 holders · as of Aug 26, 2026
Other72.22%6.51M shares
remainder

9.01M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesDate
Branham Justin EarlInsider
5.13%462,148filed Aug 26, 2026
David J. MazzoInsiderdirector, officer: President & CEO
3.46%311,890filed Jan 13, 2026
Vanguard Capital Management LLCInstitution
3.09%278,837as of Jun 30, 2026
Yakira Capital Management, Inc.Institution
1.54%138,561as of Jun 30, 2026
CSS LLC/ILInstitution
1.23%110,422as of Jun 30, 2026

Insider tradesForm 4

No open-market trades in the last 12 months.

View details

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Compare

CompanyPriceChange
Lisata Therapeutics$1.45−2.03%$13.5M134.8−90.0%
AstraZeneca (ADR)$163.75−2.74%$261.12B25.315.44.3+6.4%
Merck$147.55−2.23%$372.73B120.717.15.6+5.1%
Novocure$16.09−3.48%$1.94B2.8+15.6%
Incyte$124.70−1.76%$25.73B16.251.64.4+37.7%
Median25.317.14.3+11.0%