Milestone Scientific (MLSS)
Computer-controlled dental and epidural injection systems with pressure feedback.
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Builds computer-controlled dental-anesthesia and epidural-injection systems using Dynamic Pressure Sensing, earning revenue from instruments and single-use handpieces. Dental supplies nearly all product sales, while Medical commercialization depends on adoption, reimbursement, and regulatory clearance.
Builds computer-controlled injection systems using Dynamic Pressure Sensing, which regulates fluid flow and measures pressure at the needle tip in real time. Dental offerings include CompuDent and the STA Single Tooth Anesthesia System with single-use The Wand handpieces; Medical offerings include CompuFlo Epidural and CathCheck.
Earns revenue from instruments and recurring handpieces. Dental sales reach U.S. offices directly through e-commerce and distributors abroad, while Medical uses a direct-and-agent U.S. model and third-party distributors internationally. Manufacturing is outsourced, with dental handpieces sourced from China.
Operates Dental and Medical segments, with Dental providing almost all product sales. Medical adoption depends on clinician acceptance, jurisdiction-specific reimbursement, regulatory clearance, and distribution capability; the principal handpiece supplier is a related party.
Company facts
No analyst consensus on record.
EPSReportedEstimate
RevenueReportedEstimate
Balance sheet, Jun 30, 2026Cash & short-term investments $2.1M · Total debt $615.7K · Total assets $8.3M · Shareholders' equity $3.5M
- Revenue
- $2.8M
- Operating income
- −$1.1M
- Net income
- −$1.1M
No dividends on record.
| Institutions | 6.06% | 5.38M shares | |
|---|---|---|---|
| 31 holders · as of Jun 30, 2026 | |||
| Insiders | 10.90% | 9.67M shares | |
| 1 holder · as of Feb 7, 2025 | |||
| Other | 83.04% | 73.69M shares | |
| remainder | |||
88.74M company shares as of Sep 22, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing
Top shareholders13F · 13D/G · Form 4
| Holder | Stake | Shares | Date |
|---|---|---|---|
Bp4 S.r.l.Insider | 10.90% | 9.67M | filed Feb 7, 2025 |
Vanguard Capital Management LLCInstitution | 2.34% | 2.07M | as of Jun 30, 2026 |
Stonepine Capital Management, LLCInstitution | 0.75% | 666,666 | as of Jun 30, 2026 |
Geode Capital Management, LLCInstitution | 0.73% | 643,611 | as of Jun 30, 2026 |
Vanguard Fiduciary Trust CoInstitution | 0.52% | 464,449 | as of Jun 30, 2026 |
Insider tradesForm 4
Nothing filed in the last 12 months.
- Dentsply Sirona
Computer-controlled dental anesthesia for the same practices.
- BD
Conventional epidural trays and loss-of-resistance workflow.
- Teleflex
Epidural catheter trays and loss-of-resistance workflow.
Compare
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| Milestone Scientific | $0.4217 | +7.91% | $34.6M | — | — | 3.7 | +22.3% |
| Dentsply Sirona | $9.86 | +4.40% | $1.89B | — | 6.7 | 0.5 | −4.1% |
| BD | $181.88 | +0.65% | $49.79B | 54.4 | 13.7 | 2.4 | −9.6% |
| Teleflex | $124.96 | +0.13% | $5.52B | — | 13.5 | 2.1 | −27.0% |
| Median | 54.4 | 13.5 | 2.1 | −9.6% |






