OBIO · NASDAQ · Biotechnology

Orchestra BioMed (OBIO)

Develops partnership-enabled device therapies for hypertension and artery disease.

$5.94
vs last close−0.28 (−4.50%)

13F · 13D/G · Form 4

Institutions46.66%28.04M shares
81 holders · as of Jun 30, 2026
Insiders6.13%3.69M shares
10 holders · as of Sep 11, 2026
Strategic holders21.51%12.93M shares
2 holders · as of Feb 27, 2026
Other25.70%15.45M shares
remainder

60.11M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

13F · 13D/G · Form 4

HolderStakeSharesDate
Medtronic plc1,2Strategic10 percent owner
16.77%10.08Mfiled Feb 27, 2026
RTW Investments, LPInstitution
15.90%9.56Mas of Jun 30, 2026
Perceptive Advisors LLCInstitution
8.38%5.04Mas of Jun 30, 2026
Tasso Partners, LLCStrategic
4.74%2.85Mfiled Nov 19, 2025
BlackRock, Inc.Institution
4.18%2.51Mas of Jun 30, 2026
Vanguard Capital Management LLCInstitution
3.37%2.02Mas of Jun 30, 2026
David P. HochmanInsiderdirector, officer: See Remarks
2.50%1.50Mfiled Sep 11, 2026
Darren ShermanInsiderdirector, officer: See Remarks
1.89%1.14Mfiled Sep 2, 2026
Geode Capital Management, LLCInstitution
1.68%1.01Mas of Jun 30, 2026
Alyeska Investment Group, L.P.Institution
1.66%1.00Mas of Jun 30, 2026
Propel Bio Management, LLCInstitution
1.49%896,701as of Jun 30, 2026
UBS Asset Management Americas IncInstitution
1.07%642,154as of Jun 30, 2026
Andrew Lawrence TaylorInsiderofficer: Chief Financial Officer
0.98%589,989filed Aug 28, 2026
State Street CorpInstitution
0.86%516,050as of Jun 30, 2026
Rice Hall James & Associates, LLCInstitution
0.71%424,000as of Jun 30, 2026
Charles Schwab Investment Management IncInstitution
0.58%349,544as of Jun 30, 2026
Sixth Street Partners Management Company, L.P.Institution
0.58%349,544as of Jun 30, 2026
Northern Trust CorpInstitution
0.57%343,640as of Jun 30, 2026
UBS Group AGInstitution
0.54%325,773as of Jun 30, 2026
Vanguard Fiduciary Trust CoInstitution
0.49%292,253as of Jun 30, 2026
Vanguard Portfolio Management LLCInstitution
0.46%274,973as of Jun 30, 2026
Knott David M JrInstitution
0.42%253,651as of Jun 30, 2026
Flat Footed LLCInstitution
0.42%251,372as of Jun 30, 2026
Simplify Asset Management Inc.Institution
0.37%219,387as of Jun 30, 2026
Goldman Sachs Group IncInstitution
0.30%179,606as of Jun 30, 2026
  1. Medtronic plc's transaction reports restate only vehicles that traded; the 2026 ownership statement (10.08M) is used instead.
  2. Medtronic plc reports a block also reported by Perceptive Advisors LLC; it is counted once, under Perceptive Advisors LLC.

13F, as of Jun 30, 2026

81 holders · 28.04M shares · 26 new positions · 48 increased · 15 reduced · 13 closed

HolderShares% outstandingChg q/qFiled
RTW Investments, LP9.56M15.90%+1.25MAug 14, 2026
Perceptive Advisors LLC5.04M8.38%0Aug 14, 2026
BlackRock, Inc.2.51M4.18%+1.87MAug 7, 2026
Vanguard Capital Management LLC2.02M3.37%−181.4KAug 13, 2026
Geode Capital Management, LLC1.01M1.68%+522.4KAug 12, 2026
Alyeska Investment Group, L.P.1.00M1.66%0Aug 14, 2026
Propel Bio Management, LLC896.7K1.49%0Aug 13, 2026
UBS Asset Management Americas Inc642.2K1.07%+642.2KnewAug 13, 2026

13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Roderick Wongincl. RTW Innovation Master Fund, Ltd., RTW Investments, LP +1 more19.20%11.94M13DApr 29, 2026
Medtronic plc17.80%10.08M13GFeb 27, 2026
Perceptive Advisors LLC9.99%5.68M13GNov 14, 2025
BlackRock, Inc.5.10%1.94MNov 8, 2024
Tasso Partners, LLC5.00%2.85M13GNov 19, 2025

Form 4

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Sep 3, 2026
David P. Hochmandirector, officer: See Remarks
Purchase10,000$4.791,070,746
Sep 1, 2026
Darren Shermandirector, officer: See Remarks
Sale15,000$4.941,134,402
Aug 26, 2026
Darren Shermandirector, officer: See Remarks
Purchase2,000$5.332,000
Aug 3, 2026
Darren Shermandirector, officer: See Remarks
Sale15,000$4.091,154,327
Jul 1, 2026
Darren Shermandirector, officer: See Remarks
Sale15,000$4.271,169,327
Jun 1, 2026
Darren Shermandirector, officer: See Remarks
Sale15,000$3.871,184,327
Jun 1, 2026
David P. Hochmandirector, officer: See Remarks
Purchase5,000$3.831,064,029
May 18, 2026
Jason Aryehdirector
Purchase665$3.75118,118
May 15, 2026
David P. Hochmandirector, officer: See Remarks
Purchase5,000$3.771,059,029
May 15, 2026
Jason Aryehdirector
Purchase8,971$3.90117,453

House and Senate disclosures

Not reported.