PACB · NASDAQ · Medical - Devices

PacBio (PACB)

Builds HiFi sequencing platforms centered on Revio, Vega, and consumables.

$1.46
vs last close+0.09 (+6.99%)
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Pacific Biosciences of California, Inc.PACB
Health Care

Sells long-read sequencing instruments, consumables, software, and services for genomic analysis. Consumables are the largest revenue category, and the business is refocused on HiFi long-read adoption after selling selected short-read assets.

Sells Revio and Vega sequencing systems, SMRT Cells, chemistry, sample-prep kits, software, and services built around SMRT and HiFi long-read sequencing. Customers include research institutions, service labs, public health groups, pharmaceutical companies, and agriculture users.

Revenue is reported as a single genetic-analysis platform segment across instruments, consumables, and service or other offerings. Sales span the Americas, EMEA, and Asia-Pacific, with the United States forming most of the Americas line.

Execution depends on expanding the installed base, repeat consumables use, and clinical-research adoption of HiFi sequencing. Products are generally research-use-only unless regulatory status changes, and many customers buy through purchase orders rather than long-term volume commitments.

Company facts

CEOChristian O. Henry
ListedOct 27, 2010
ExchangeNASDAQ
HeadquartersMenlo Park, CA
CountryUnited States
Employees485
CIK0001299130
ISINUS69404D1081

Market cap$422.4M
EPS (ttm)−$0.4300
P/E (ttm)−3.16
ROE-4,961.7%
P/B
P/S2.65
Dividend yieldDiv yield
Beta2.45vs XLV 0.85

Price target$1.18−13.6%Average of 18 analysts
ConsensusBuy9 of 18 analysts
Ratings

Target rangeAs of Sep 21, 2026

Latest analyst notes

DateFirmActionPriorCurrent
Sep 9, 2026UBSTarget
Target:
Target: $1.35
Apr 14, 2026BarclaysReiterate
Rating: Target: $1.50
Rating: UnderweightTarget: $1
Mar 6, 2026BarclaysDowngrade
Rating: Equal Weight
Rating: Underweight
Nov 11, 2024UBSDowngrade
Rating: Buy
Rating: Neutral

Next report
Nov 3, 26
in 42 days
EPS estimate
−$0.13
Revenue estimate
$43.8M
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Feb '25May '25Aug '25Nov '25Feb '26May '26Aug '26Nov '26
Reported−$0.20−$1.44−$0.13−$0.12−$0.12−$0.03−$0.14Pending
Estimate−$0.20−$0.19−$0.18−$0.16−$0.19−$0.17−$0.13−$0.13
Surprise0.0%−657.9%+27.8%+25.0%+36.8%+82.4%−9.4%

RevenueReportedEstimate

Feb '25May '25Aug '25Nov '25Feb '26May '26Aug '26Nov '26
Reported$39.2M$37.2M$39.8M$38.4M$44.6M$37.2M$39.0MPending
Estimate$40.7M$35.4M$39.9M$44.6M$43.0M$39.9M$42.9M$43.8M
Surprise−3.6%+4.8%−0.5%−13.8%+3.7%−6.9%−9.1%
Estimate−$0.13
ReportedDue Nov 3, 2026
Estimate$43.8M
ReportedDue Nov 3, 2026
View details

Current ratio492.20%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$40.0M$39.2M$37.2M$39.8M$38.4M$44.6M$37.2M$39.0M
Net income−$60.7M$2.4M−$426.1M−$41.9M−$38.0M−$40.4M−$8.3M−$44.7M
Net margin0.0%6.0%0.0%0.0%0.0%0.0%0.0%0.0%

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$64.1M−$153.0M−$428.9M−$44.9M−$38.8M−$41.2M−$37.9M−$44.6M
YoY growthLoss narrowedLoss widenedLoss widenedLoss narrowedLoss narrowedLoss narrowedLoss narrowedLoss narrowed

Balance sheet, Jun 30, 2026Cash & short-term investments $236.9M · Total debt $706.1M · Total assets $751.9M · Shareholders' equity −$33.2M

Revenue
$39.0M
Operating income
−$44.6M
Net income
−$44.7M
View details

No dividends on record.

Institutions62.33%193.74M shares
229 holders · as of Jun 30, 2026
Insiders1.93%5.99M shares
6 holders · as of Apr 10, 2026
Other35.74%111.09M shares
remainder

310.83M company shares as of Sep 22, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesDate
BlackRock, Inc.Institution
10.40%32.34Mas of Jun 30, 2026
Ark Investment Management LLCInstitution
9.58%29.78Mas of Jun 30, 2026
SoftBank Group Corp.Institution
6.58%20.45Mas of Jun 30, 2026
Vanguard Capital Management LLCInstitution
4.31%13.40Mas of Jun 30, 2026
Geode Capital Management, LLCInstitution
2.45%7.61Mas of Jun 30, 2026

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Aug 17, 2026Mark van Oeneofficer: See Remarks−26,911$1.13
Apr 1, 2026James R. II Gibsonofficer: See Remarks−88,185$1.37
Mar 3, 2026Michele Farmerofficer: See Remarks−2,979$1.51
Mar 3, 2026Mark van Oeneofficer: See Remarks−6,504$1.51
Mar 3, 2026Christian O. Henryofficer: See Remarks−12,497$1.51
View details

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