Praxis Precision Medicines (PRAX)
Develops small-molecule and antisense therapies for essential tremor and genetic epilepsies.
$282.29
vs last close−18.36 (−6.11%)
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13F · 13D/G · Form 4
| Institutions | ≈ 120.49% | 33.64M shares | |
|---|---|---|---|
| 330 holders · as of Jun 30, 2026 · largest filers plus last quarter's tail | |||
| Insiders | 0.68% | 189.5K shares | |
| 13 holders · as of Jul 8, 2026 | |||
| Strategic holders | 89.25% | 24.92M shares | |
| 2 holders · as of Nov 14, 2025 | |||
| Adds to | 210.42% | ||
27.92M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing
This quarter's institutional total failed a plausibility check; shown: the largest filers plus last quarter's remainder.
These groups come from separate filings that can overlap, so they add to 210.42%; nothing is left for Other.
13F, as of Jun 30, 2026
330 holders · 33.64M shares · 60 new positions · 183 increased · 98 reduced · 44 closed
| Holder | Shares | % outstanding | Chg q/q | Filed |
|---|---|---|---|---|
| Jupiter Topco LLC | 3.42M | 12.25% | +3.42Mnew | Aug 14, 2026 |
| FMR LLC | 2.32M | 8.30% | +156.0K | Aug 13, 2026 |
| BlackRock, Inc. | 2.29M | 8.21% | −32.3K | Aug 7, 2026 |
| Perceptive Advisors LLC | 2.04M | 7.29% | 0 | Aug 14, 2026 |
| Baker Bros. Advisors LP | 1.75M | 6.28% | 0 | Aug 14, 2026 |
| Orbis Allan Gray Ltd | 1.53M | 5.48% | −942.7K | Aug 14, 2026 |
| Vanguard Portfolio Management LLC | 1.34M | 4.78% | +578.4K | Aug 13, 2026 |
| Vanguard Capital Management LLC | 1.24M | 4.42% | +13.4K | Aug 13, 2026 |
13D/G · 5% or more, as filed
| Holder | % of class | Shares | Form | Filed |
|---|---|---|---|---|
| Janus Henderson Group PLC | 12.30% | 2.76M | 13G | Nov 14, 2025 |
| Orbis Investment Management Ltd | 8.90% | 2.47M | 13G | May 15, 2026 |
| FMR LLC | 7.70% | 2.16M | 13G | May 6, 2026 |
| BlackRock, Inc. | 7.30% | 1.30M | Nov 8, 2024 | |
| Perceptive Advisors LLC | 7.20% | 2.00M | 13G | Feb 17, 2026 |
| Baker Bros. Advisors LP | 6.30% | 1.75M | 13G | May 15, 2026 |
| Vanguard Capital Management | 5.09% | 1.42M | 13G | Apr 30, 2026 |
Form 4
Latest trades
| Date | Insider | Type | Shares | Avg price | Owned after |
|---|---|---|---|---|---|
| Jun 24, 2026 | Jill DeSimonedirector | Sale · 12 lots | 11,600 | $311.32 | 2,337 |
| Nov 20, 2025 | Lauren Mastrocolaofficer: Principal Accounting Officer | Sale · 2 lots | 13,600 | $192.08 | 10,442 |
| Nov 20, 2025 | Alex Nemiroffofficer: General Counsel and Secretary | Sale · 4 lots | 25,130 | $193.09 | 20,832 |
| Oct 16, 2025 | Adage Capital Management, L.P.10 percent owner | Sale · 10 lots | 313,910 | $105.76 | 4,421,660 |
House and Senate disclosures
| Member | Type | Amount | Owner | Traded | Disclosed |
|---|---|---|---|---|---|
| Rep. Gilbert Ray Cisneros · CA31 | Purchase | $1,001 – $15,000 | Jul 30, 2026 | Sep 7, 2026 | |
| Rep. Gilbert Ray Cisneros · CA31 | Purchase | $1,001 – $15,000 | Jul 29, 2026 | Sep 7, 2026 |