Prelude Therapeutics (PRLD)
Develops small-molecule oncology programs centered on JAK2V617F inhibition and KAT6A degradation.
$4.28
vs last close−0.57 (−11.75%)
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13F · 13D/G · Form 4
| Institutions | 62.24% | 49.67M shares | |
|---|---|---|---|
| 83 holders · as of Jun 30, 2026 | |||
| Insiders | 1.05% | 837.0K shares | |
| 5 holders · as of Mar 19, 2026 | |||
| Other | 36.71% | 29.30M shares | |
| remainder | |||
79.80M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing
13F, as of Jun 30, 2026
83 holders · 49.67M shares · 36 new positions · 62 increased · 9 reduced · 12 closed
| Holder | Shares | % outstanding | Chg q/q | Filed |
|---|---|---|---|---|
| Orbimed Advisors LLC | 13.72M | 17.20% | +2.82M | Aug 14, 2026 |
| Baker Bros. Advisors LP | 10.12M | 12.69% | 0 | Aug 14, 2026 |
| Ra Capital Management, L.P. | 6.48M | 8.11% | +6.48Mnew | Aug 14, 2026 |
| Soleus Capital Management, L.P. | 3.38M | 4.23% | +3.38Mnew | Aug 11, 2026 |
| Kynam Capital Management, LP | 2.42M | 3.03% | +822.5K | Aug 14, 2026 |
| Vanguard Capital Management LLC | 2.01M | 2.52% | +779.0K | Aug 13, 2026 |
| BlackRock, Inc. | 1.80M | 2.25% | +1.48M | Aug 7, 2026 |
| Sphera Funds Management Ltd. | 1.02M | 1.28% | +461.5K | Aug 14, 2026 |
13D/G · 5% or more, as filed
| Holder | % of class | Shares | Form | Filed |
|---|---|---|---|---|
| Orbimed Advisors LLCincl. OrbiMed Genesis GP LLC, Orbimed Capital GP Vi LLC +1 more | 16.00% | 12.94M | 13D | Apr 23, 2026 |
| Baker Bros. Advisors (GP) LLCincl. Julian C. Baker, Baker Bros. Advisors LP +1 more | 15.50% | 10.30M | 13D | Apr 22, 2026 |
| Vaddi Krishna | 13.15% | 6.75M | 13G | Feb 13, 2026 |
| RA Capital Management, L.P. | 9.90% | 6.48M | 13G | Apr 28, 2026 |
| Incyte Corp | 9.90% | 4.37M | 13G | Nov 7, 2025 |
Form 4
Latest trades
| Date | Insider | Type | Shares | Avg price | Owned after |
|---|---|---|---|---|---|
| Apr 21, 2026 | Orbimed Advisors LLCdirector, 10 percent owner: | Purchase · 2 lots | 2,815,315 | $4.44 | 11,808,945 |
| Apr 21, 2026 | David P. Bonitadirector, 10 percent owner: | Purchase · 2 lots | 2,815,315 | $4.44 | 11,808,945 |
| Apr 21, 2026 | Baker Bros. Advisors LPdirector, 10 percent owner: | Purchase · 2 lots | 2,252,252 | $0.0001 | 20,105,994 |
House and Senate disclosures
Not reported.