PRTA · NASDAQ · Biotechnology

Prothena (PRTA)

Develops investigational protein-dysregulation therapies with a partner-heavy clinical pipeline.

$8.69
vs last close−0.30 (−3.29%)

13F · 13D/G · Form 4

Institutions92.75%47.62M shares
197 holders · as of Jun 30, 2026
Insiders20.43%10.49M shares
11 holders · as of Sep 21, 2026
Strategic holders10.33%5.30M shares
1 holder · as of May 6, 2025
Adds to123.51%

51.34M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

These groups come from separate filings that can overlap, so they add to 123.51%; nothing is left for Other.

13F · 13D/G · Form 4

HolderStakeSharesDate
FMR LLCInstitution
14.02%7.20Mas of Jun 30, 2026
William P. Scully1Insider10 percent owner
10.86%5.38Mfiled Sep 21, 2026
EcoR1 Capital, LLCStrategic10 percent owner
10.33%5.30Mfiled May 6, 2025
Rubric Capital Management LPInstitution
9.74%5.00Mas of Jun 30, 2026
BlackRock, Inc.Institution
9.48%4.87Mas of Jun 30, 2026
Fennell Todd W.Insider
8.76%4.50Mfiled Nov 12, 2025
Patient Capital TrustInstitution
4.84%2.48Mfiled Feb 14, 2019
State Street CorpInstitution
4.66%2.39Mas of Jun 30, 2026
OrbiMed Capital LLCInstitution
4.46%2.29Mfiled Feb 14, 2020
Acadian Asset Management LLCInstitution
3.92%2.01Mas of Jun 30, 2026
Vanguard Portfolio Management LLCInstitution
3.22%1.65Mas of Jun 30, 2026
D. E. Shaw & Co., Inc.Institution
3.14%1.61Mas of Jun 30, 2026
Adar1 Capital Management, LLCInstitution
3.03%1.55Mas of Jun 30, 2026
Two Sigma Investments, LPInstitution
2.46%1.26Mas of Jun 30, 2026
Palo Alto Investors LPInstitution
2.23%1.14Mas of Jun 30, 2026
Geode Capital Management, LLCInstitution
2.19%1.13Mas of Jun 30, 2026
Federated Hermes, Inc.Institution
2.11%1.08Mas of Jun 30, 2026
Morgan StanleyInstitution
1.94%995,348as of Jun 30, 2026
Goldman Sachs Group IncInstitution
1.91%979,730as of Jun 30, 2026
Jacobs Levy Equity Management, IncInstitution
1.88%965,988as of Jun 30, 2026
Dimensional Fund Advisors LPInstitution
1.76%905,651as of Jun 30, 2026
Qube Research & Technologies LtdInstitution
1.54%791,169as of Jun 30, 2026
Renaissance Technologies LLCInstitution
1.36%697,615as of Jun 30, 2026
Man Group PLCInstitution
1.32%678,116as of Jun 30, 2026
Mariner, LLCInstitution
1.22%625,095as of Jun 30, 2026
  1. William P. Scully's transaction reports restate only vehicles that traded; the 2026 ownership statement (5.38M) plus the 194.5K net shares acquired since is used instead.

13F, as of Jun 30, 2026

197 holders · 47.62M shares · 31 new positions · 89 increased · 58 reduced · 24 closed

HolderShares% outstandingChg q/qFiled
FMR LLC7.20M14.02%−352.0KAug 13, 2026
Rubric Capital Management LP5.00M9.74%0Aug 14, 2026
BlackRock, Inc.4.87M9.48%+223.8KAug 7, 2026
State Street Corp2.39M4.66%+454.9KAug 7, 2026
Acadian Asset Management LLC2.01M3.92%+463.1KAug 13, 2026
Vanguard Portfolio Management LLC1.65M3.22%+205.3KAug 13, 2026
D. E. Shaw & Co., Inc.1.61M3.14%−151.9KAug 14, 2026
Adar1 Capital Management, LLC1.55M3.03%−26.9KAug 14, 2026

13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Scully William P10.30%5.38M13GMay 11, 2026
Rubric Capital Management LP9.29%5.00M13GMay 15, 2026
Fennell Todd W.8.40%4.50M13GNov 12, 2025
BlackRock, Inc.5.70%3.09M13GOct 17, 2025

Form 4

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Sep 18, 2026
William P. Scully10 percent owner
Purchase100,000$8.43927,000
Sep 2, 2026
William P. Scully10 percent owner
Purchase27,000$9.47827,000
Aug 20, 2026
William P. Scully10 percent owner
Purchase50,000$8.79800,000
Aug 7, 2026
William P. Scully10 percent owner
Purchase · 2 lots37,500$8.62873,500
Jul 29, 2026
Michael John Isaacsofficer: General Counsel & Company Sec.
Sale8,386$8.4735,745
Jul 29, 2026
Anne Evans Kingstonofficer: Chief Strategy Officer
Sale7,662$8.4755,782
Jun 16, 2026
William P. Scully10 percent owner
Purchase20,000$7.90756,000
Jun 11, 2026
William P. Scully10 percent owner
Purchase125,000$8.171,061,000
Jun 4, 2026
William P. Scully10 percent owner
Purchase50,000$9.31936,000
Jun 2, 2026
William P. Scully10 percent owner
Purchase50,000$9.43886,000

House and Senate disclosures

Not reported.