PTHS · AMEX · Biotechnology

Pelthos Therapeutics (PTHS)

Commercializes topical treatments for molluscum, impetigo, and head lice.

$23.85
vs last close+0.61 (+2.62%)
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Pelthos Therapeutics Inc.PTHS
Health Care

Sells ZELSUVMI, an at-home topical treatment for molluscum contagiosum, while preparing XEPI for impetigo and XEGLYZE for head lice. Combines U.S. commercial operations with in-house active-ingredient manufacturing while licensing core NITRICIL intellectual property from Ligand.

Commercializes topical treatments for cutaneous infectious diseases, beginning with ZELSUVMI, an at-home nitric-oxide-releasing gel for molluscum contagiosum. XEPI for impetigo and XEGLYZE for head lice are FDA-approved acquired products in launch preparation, while CT2000 remains an early clinical program for eye pain.

Operates an in-house U.S. sales and market-access organization and manufactures ZELSUVMI's active ingredient in Durham; finished-drug production, logistics, and wholesale distribution rely on third parties. Revenue is currently tied to ZELSUVMI, with adoption dependent on physician and patient acceptance, pharmacy-benefit coverage, reimbursement, and sales-force execution. Core NITRICIL intellectual property is licensed from Ligand.

Company facts

CEOScott M. Plesha
ListedJul 2, 2025
ExchangeAMEX
HeadquartersDurham, NC
CountryUnited States
Employees92
CIK0001919246
ISINUS1711262048

Market cap$80.8M
EPS (ttm)−$41.93
P/E (ttm)−0.5543
ROE-218.9%
P/B
P/S1.87
Dividend yieldDiv yield
Beta0.47vs XLV 0.14

Price target$54.50+134.5%Average of 3 analysts
ConsensusBuy3 of 3 analysts
Ratings

Target rangeAs of Sep 22, 2026

Latest analyst notes

DateFirmActionPriorCurrent
Aug 14, 2026OppenheimerReiterate
Rating: Target: $66
Rating: OutperformTarget: $64
Aug 13, 2026Industrial Alliance SecuritiesTarget
Target:
Target: $45
May 15, 2026OppenheimerTarget
Target:
Target: $66

Next report
Nov 12, 26
in 50 days
EPS estimate
−$2.90
Revenue estimate
$18.0M
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported−$3.23−$3.21−$5.38−$5.30−$6.87−$3.09−$6.62Pending
Estimate−$2.90−$5.82−$0.67−$3.95−$3.45−$2.82−$2.90
Surprise−10.7%+7.6%−691.0%−73.9%+10.4%−134.8%

RevenueReportedEstimate

Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported$150.0K$7.4M$9.4M$10.9M$15.6MPending
Estimate$4.4M$4.4M$9.1M$10.4M$15.2M$18.0M
Surprise+68.7%+3.3%+4.5%+2.8%
Estimate−$2.90
ReportedDue Nov 12, 2026
Estimate$18.0M
ReportedDue Nov 12, 2026
View details

Current ratio198.20%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0$0$0$7.4M$9.4M$10.9M$15.6M
Net income−$1.7M−$1.9M−$2.0M−$3.4M−$16.2M−$21.7M−$10.2M−$23.4M
Net margin0.0%0.0%0.0%0.0%

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$2.0M−$1.8M−$1.8M−$3.2M−$15.4M−$12.0M−$13.1M−$17.3M
YoY growthLoss narrowedLoss narrowedLoss widenedLoss widenedLoss widenedLoss widenedLoss widened

Balance sheet, Jun 30, 2026Cash & short-term investments $24.6M · Total debt $73.1M · Total assets $137.4M · Shareholders' equity −$1.5M

Revenue
$15.6M
Operating income
−$17.3M
Net income
−$23.4M
View details

No dividends on record.

Institutions38.07%1.32M shares
23 holders · as of Jun 30, 2026
Other61.93%2.15M shares
remainder

3.48M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesDate
Aigh Capital Management LLCInstitution
9.47%329,098as of Jun 30, 2026
Murchinson Ltd.Institution
8.76%304,302as of Jun 30, 2026
Ikarian Capital, LLCInstitution
7.38%256,598as of Jun 30, 2026
Boothbay Fund Management, LLCInstitution
2.93%101,976as of Jun 30, 2026
Vanguard Capital Management LLCInstitution
2.79%97,134as of Jun 30, 2026

Insider tradesForm 4

Nothing filed in the last 12 months.

View details

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CompanyPriceChange
Pelthos Therapeutics$23.85+2.62%$80.8M1.9
Verrica Pharmaceuticals$4.67−1.06%$81.1M2.7−53.9%
Perrigo$14.13−1.26%$1.98B6.00.5−3.2%
Median6.01.6−28.5%