SION · NASDAQ · Biotechnology

Sionna Therapeutics (SION)

Develops NBD1-stabilizing and complementary CFTR modulators for cystic fibrosis.

$5.59
vs last close−0.43 (−7.23%)

13F · 13D/G · Form 4

Institutions≈ 106.37%48.09M shares
157 holders · as of Jun 30, 2026 · largest filers plus last quarter's tail
Insiders2.04%924.1K shares
4 holders · as of Sep 18, 2026
Strategic holders8.17%3.69M shares
1 holder · as of Feb 10, 2025
Adds to116.58%

45.21M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

This quarter's institutional total failed a plausibility check; shown: the largest filers plus last quarter's remainder.

These groups come from separate filings that can overlap, so they add to 116.58%; nothing is left for Other.

13F · 13D/G · Form 4

HolderStakeSharesDate
Ra Capital Management, L.P.Institution
21.91%9.91Mas of Jun 30, 2026
TPG GP A, LLCInstitution
14.37%6.49Mas of Jun 30, 2026
Atlas Venture Fund XI, L.P.Strategic10 percent owner
8.17%3.69Mfiled Feb 10, 2025
Viking Global Investors LPInstitution
7.07%3.20Mas of Jun 30, 2026
Atlas Venture Life Science Advisors, LLCInstitution
6.63%3.00Mas of Jun 30, 2026
Orbimed Advisors LLCInstitution
5.65%2.56Mas of Jun 30, 2026
Enavate Sciences GP, LLCInstitution
5.48%2.48Mas of Jun 30, 2026
Adage Capital Partners GP, L.L.C.Institution
3.54%1.60Mas of Jun 30, 2026
JPMorgan Chase & CoInstitution
3.30%1.49Mas of Jun 30, 2026
BlackRock, Inc.Institution
3.26%1.47Mas of Jun 30, 2026
Jennison Associates LLCInstitution
2.59%1.17Mas of Jun 30, 2026
Citadel Advisors LLCInstitution
2.54%1.15Mas of Jun 30, 2026
Vanguard Capital Management LLCInstitution
2.50%1.13Mas of Jun 30, 2026
State Street CorpInstitution
2.26%1.02Mas of Jun 30, 2026
Perceptive Advisors LLCInstitution
2.00%905,000as of Jun 30, 2026
Deerfield Management Company, L.P. (Series C)Institution
1.51%680,916as of Jun 30, 2026
Michael CloonanInsiderdirector, officer: President & CEO
1.45%656,368filed Sep 18, 2026
Siren, L.L.C.Institution
1.35%610,515as of Jun 30, 2026
Price T Rowe Associates Inc /MD/Institution
1.06%478,016as of Jun 30, 2026
Eventide Asset Management, LLCInstitution
1.05%474,981as of Jun 30, 2026
Geode Capital Management, LLCInstitution
1.01%457,145as of Jun 30, 2026
Baker Bros. Advisors LPInstitution
0.88%400,000as of Jun 30, 2026
Casdin Capital, LLCInstitution
0.88%400,000as of Jun 30, 2026
Goldman Sachs Group IncInstitution
0.86%388,810as of Jun 30, 2026
Driehaus Capital Management LLCInstitution
0.85%385,447as of Jun 30, 2026

13F, as of Jun 30, 2026

157 holders · 48.09M shares · 41 new positions · 98 increased · 40 reduced · 9 closed

HolderShares% outstandingChg q/qFiled
Ra Capital Management, L.P.9.91M21.91%0Aug 14, 2026
TPG GP A, LLC6.49M14.37%0Aug 14, 2026
Viking Global Investors LP3.20M7.07%0Aug 14, 2026
Atlas Venture Life Science Advisors, LLC3.00M6.63%0Aug 13, 2026
Orbimed Advisors LLC2.56M5.65%−974.8KAug 14, 2026
Enavate Sciences GP, LLC2.48M5.48%0Aug 14, 2026
Adage Capital Partners GP, L.L.C.1.60M3.54%+1.45MAug 14, 2026
JPMorgan Chase & Co1.49M3.30%+25.5KAug 12, 2026

13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
TPG GP A, LLC15.20%6.68M13DFeb 18, 2025
Peter Kolchinskyincl. RA Capital Healthcare Fund, L.P., RA Capital Management, L.P. +2 more14.30%6.48M13DSep 21, 2026
Viking Global Investors LP7.10%3.20M13GMay 15, 2026
OrbiMed Capital GP VIII LLCincl. Orbimed Advisors LLC6.60%2.97M13DApr 20, 2026
Sionna Aggregator, LPincl. Enavate Sciences GP, LLC5.60%2.48M13DFeb 18, 2025
Atlas Venture Associates XI, LLCincl. Atlas Venture Opportunity Fund II, L.P., Atlas Venture Associates Opportunity II, LLC +3 more5.40%2.38M13DOct 20, 2025

Form 4

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Sep 17, 2026
Ra Capital Management, L.P.director, 10 percent owner:
Sale · 2 lots3,448,811$6.333,448,812
Jul 7, 2026
Orbimed Advisors LLCdirector
Sale85,918$44.862,469,959
Jul 7, 2026
Peter A. Thompsondirector
Sale85,918$44.862,469,959
Jul 6, 2026
Jennifer Fitzpatrickofficer: Chief Legal Officer
Sale10,250$43.600
Jun 30, 2026
Orbimed Advisors LLCdirector
Sale115,844$45.502,555,877
Jun 30, 2026
Peter A. Thompsondirector
Sale115,844$45.502,555,877
May 27, 2026
Orbimed Advisors LLCdirector
Sale101$44.492,671,721
May 27, 2026
Peter A. Thompsondirector
Sale101$44.492,671,721
May 11, 2026
Orbimed Advisors LLCdirector
Sale184,639$46.222,671,822
May 8, 2026
Orbimed Advisors LLCdirector
Sale59,767$44.582,856,461

House and Senate disclosures

Not reported.