Vogenx (VOGX)
Develops an oral SGLT1 inhibitor for post-bariatric hypoglycemia.
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Develops the oral, gut-restricted SGLT1 inhibitor mizagliflozin for post-bariatric hypoglycemia and earlier-stage metabolic and gastrointestinal indications, funding research through capital rather than product sales and depending on an in-licensed compound across most of its pipeline.
Develops mizagliflozin, an oral, minimally absorbed SGLT1 inhibitor designed to alter post-meal glucose absorption and insulin and GIP secretion. The lead program targets post-bariatric hypoglycemia, with earlier plans for gastroparesis and GIP-dependent Cushing's syndrome; VGX-2857 is a preclinical weight-maintenance combination concept. There are no approved products or commercial operations.
Operates from Raleigh with worldwide mizagliflozin rights excluding Japan, Korea and Taiwan. The company relies on Kissei's license, outsourced manufacturing, contract research organizations, clinical sites and investigators. Development is financed by equity and debt capital rather than product sales, and most of the pipeline depends on mizagliflozin.
Company facts
No analyst consensus on record.
EPSReportedEstimate
RevenueReportedEstimate
Not reported.
No dividends on record.
| Strategic holders | 13.83% | 1.92M shares | |
|---|---|---|---|
| 1 holder · as of Sep 8, 2026 | |||
| Other | 86.17% | 11.98M shares | |
| remainder | |||
13.91M company shares as of Sep 3, 2026 · holders as of their latest filing
Top shareholders13F · 13D/G · Form 4
| Holder | Stake | Shares | Date |
|---|---|---|---|
JANUS HENDERSON GROUP Ltd.Strategic | 13.83% | 1.92M | filed Sep 8, 2026 |
Insider tradesForm 4
Nothing filed in the last 12 months.
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- Eli Lilly
Large-scale GLP-1 maintenance option with Zepbound and oral Foundayo.
Compare
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| Vogenx | $26.87 | +1.13% | $369.5M | — | — | — | — |
| Amylyx Pharmaceuticals | $30.87 | −6.44% | $3.67B | — | — | — | — |
| Fractyl Health | $0.4838 | −12.51% | $87.7M | — | — | — | — |
| Eli Lilly | $1,148.27 | −1.87% | $1.10T | 39.3 | 28.1 | 13.8 | +47.7% |
| Median | 39.3 | 28.1 | 13.8 | +47.7% |