XLO · NASDAQ · Biotechnology

Xilio Therapeutics (XLO)

Develops masked immuno-oncology therapies designed to activate within tumors.

$9.04
vs last close+0.00 (+0.05%)

13F · 13D/G · Form 4

Institutions41.93%2.76M shares
26 holders · as of Jun 30, 2026
Insiders0.58%37.8K shares
5 holders · as of Mar 30, 2026
Strategic holders9.89%650.4K shares
1 holder · as of Dec 19, 2024
Other47.60%3.13M shares
remainder

6.58M company shares as of Aug 21, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

Two share counts disagree (5.78M in the company's Sep 23, 2026 report, 6.58M elsewhere); stakes use the report.

13F · 13D/G · Form 4

HolderStakeSharesDate
Bain Capital Life Sciences Fund II, L.P.Institution
10.10%664,021filed May 15, 2026
Bain Capital Life Sciences Investors, LLCInstitution
10.10%664,021as of Jun 30, 2026
Gilead Sciences, Inc.Strategic10 percent owner
9.89%650,389filed Dec 19, 2024
Orbimed Advisors LLCInstitution
9.01%592,300as of Jun 30, 2026
Frazier Life Sciences Management, L.P.Institution
6.43%422,505as of Jun 30, 2026
Stonepine Capital Management, LLCInstitution
3.44%225,994as of Jun 30, 2026
Vanguard Capital Management LLCInstitution
2.72%178,517as of Jun 30, 2026
Sio Capital Management, LLCInstitution
2.32%152,464as of Jun 30, 2026
Adage Capital Partners GP, L.L.C.Institution
1.70%111,541as of Jun 30, 2026
Merck & Co., Inc.Institution
1.61%105,982as of Jun 30, 2026
Renaissance Technologies LLCInstitution
0.98%64,153as of Jun 30, 2026
Morgan StanleyInstitution
0.87%56,954as of Jun 30, 2026
Geode Capital Management, LLCInstitution
0.59%39,055as of Jun 30, 2026
Citadel Advisors LLCInstitution
0.39%25,950as of Jun 30, 2026
Rene RussoInsiderdirector, officer: PRESIDENT AND CEO
0.35%23,244filed Jan 5, 2026
Vanguard Fiduciary Trust CoInstitution
0.34%22,594as of Jun 30, 2026
Bridgeway Capital Management, LLCInstitution
0.27%17,544as of Jun 30, 2026
Two Sigma Investments, LPInstitution
0.22%14,544as of Jun 30, 2026
Velan Capital Investment Management LPInstitution
0.22%14,285as of Jun 30, 2026
Gsa Capital Partners LLPInstitution
0.21%13,590as of Jun 30, 2026
State Street CorpInstitution
0.20%13,311as of Jun 30, 2026
Prelude Capital Management, LLCInstitution
0.18%11,600as of Jun 30, 2026
James Samuel ShannonInsiderdirector
0.15%10,000filed Mar 30, 2026
BlackRock, Inc.Institution
0.13%8,757as of Jun 30, 2026
Katarina LuptakovaInsiderofficer: CHIEF MEDICAL OFFICER
0.04%2,375filed Jan 5, 2026

13F, as of Jun 30, 2026

26 holders · 2.76M shares · 11 new positions · 15 increased · 4 reduced · 9 closed

HolderShares% outstandingChg q/qFiled
Bain Capital Life Sciences Investors, LLC664.0K10.10%0Aug 14, 2026
Orbimed Advisors LLC592.3K9.01%+592.3KnewAug 14, 2026
Frazier Life Sciences Management, L.P.422.5K6.43%0Aug 14, 2026
Stonepine Capital Management, LLC226.0K3.44%+161.8KAug 17, 2026
Vanguard Capital Management LLC178.5K2.72%+54.9KAug 13, 2026
Sio Capital Management, LLC152.5K2.32%0Aug 14, 2026
Adage Capital Partners GP, L.L.C.111.5K1.70%+111.5KnewAug 14, 2026
Merck & Co., Inc.106.0K1.61%0Aug 7, 2026

13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Gilead Sciences, Inc.19.90%13GFeb 12, 2026
GKCC, LLCincl. Yekaterina Chudnovsky15.90%13GSep 27, 2024
BCLS II Equity Opportunities, LP9.99%664.0K13GMay 15, 2026
Orbimed Advisors LLC9.99%642.0K13GMay 15, 2026
Coastlands Capital LP9.99%13GDec 11, 2025
Sirenia Capital Management LP9.90%1.14M13GMay 15, 2026
AbbVie Inc.9.00%13GFeb 18, 2025
StemPoint Capital LP8.40%13GFeb 17, 2026
Frazier Life Sciences Public Fund, L.P.6.70%13GFeb 13, 2026

Form 4

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Mar 26, 2026
James Samuel Shannondirector
Purchase5,000$8.7910,000
Feb 13, 2026
Gilead Sciences, Inc.10 percent owner
Purchase3,739,000$0.000140,384,266
Jan 2, 2026
Christopher James Frankenfieldofficer: Chief Financial Officer
Sale7,030$0.643224,766
Jan 2, 2026
Kevin M. Brennanofficer: SVP, FINANCE AND ACCOUNTING
Sale1,826$0.64326,371

House and Senate disclosures

Not reported.