Eloxx Pharmaceuticals (ELOX)
Develops ribosome-modulating medicines for nonsense-mutation kidney diseases.
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Develops ribosome-modulating medicines for patients with nonsense mutations, centered on injectable exaluren for genetic kidney disease. It has no approved products or product sales; proprietary value depends on clinical development and regulatory approval, while partnered rare-skin-disease economics depend on Almirall.
Develops ribosome-modulating small molecules for genetic diseases caused by nonsense mutations. Its proprietary candidate, exaluren, is an injectable treatment designed to restore full-length collagen in mutation-defined Alport syndrome and is also being planned for a subset of autosomal dominant polycystic kidney disease.
Operates across the United States, Israel, and Australia through a remote, lean organization that relies on contract research and manufacturing providers. An oral agent for rare skin diseases is licensed to Almirall; prospective partner milestones and royalties depend on Almirall's development, regulatory, and commercial execution. Exaluren development depends on clinical results, regulatory acceptance of endpoints, and enrollment of genetically eligible patients.
Company facts
Target rangeAs of Sep 22, 2026
Latest analyst notes
| Date | Firm | Action | Prior | Current |
|---|---|---|---|---|
| Sep 18, 2026 | Leerink Partners | Target | Target: — | Target: $32 |
| Aug 20, 2026 | Loop Capital Markets | Target | Target: — | Target: $38 |
| Jul 19, 2026 | Guggenheim | Initiate | Rating: —Target: — | Target: $43 |
EPSReportedEstimate
RevenueReportedEstimate
Balance sheet, Jun 30, 2026Cash & short-term investments $62.0M · Total debt $0 · Total assets $63.4M · Shareholders' equity $46.4M
- Revenue
- $0
- Operating income
- −$4.5M
- Net income
- −$4.5M
No dividends on record.
| Institutions | 61.93% | 2.50M shares | |
|---|---|---|---|
| 22 holders · as of Jun 30, 2026 | |||
| Insiders | 13.76% | 555.5K shares | |
| 2 holders · as of Aug 14, 2026 | |||
| Strategic holders | 31.09% | 1.25M shares | |
| 2 holders · as of Jul 27, 2026 | |||
| Adds to | 106.78% | ||
4.04M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing
Two share counts disagree (4.04M in the company's Sep 23, 2026 report, 3.44M elsewhere); stakes use the report.
A stock split fell inside the quarter, so quarter-on-quarter changes are not shown.
These groups come from separate filings that can overlap, so they add to 106.78%; nothing is left for Other.
Top shareholders13F · 13D/G · Form 4
| Holder | Stake | Shares | Date |
|---|---|---|---|
Domicilium Capital Partners LLCStrategic | 21.18% | 854,973 | filed Jun 17, 2026 |
Coastlands Capital LPInstitution | 10.17% | 410,530 | filed Jun 17, 2026 |
Abrdn PLCInstitution | 9.91% | 400,000 | as of Jun 30, 2026 |
Aberdeen Group plcStrategic | 9.91% | 400,000 | filed Jul 27, 2026 |
Ecor1 Capital, LLCInstitution | 9.91% | 400,000 | as of Jun 30, 2026 |
Insider tradesForm 4
Nothing filed in the last 12 months.
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Compare
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| Eloxx Pharmaceuticals | $14.72 | −12.04% | $57.5M | — | — | — | — |
| Vertex Pharmaceuticals | $511.95 | −0.59% | $130.71B | 30.0 | 26.6 | 10.4 | +12.5% |
| Novartis (ADR) | $142.62 | +0.95% | $268.53B | 21.3 | 15.2 | 4.8 | +0.9% |
| Krystal Biotech | $340.20 | −3.04% | $10.34B | 44.0 | 40.0 | 23.5 | +24.1% |
| Abeona Therapeutics | $5.57 | −4.27% | $331.7M | — | — | 13.0 | +2,745.0% |
| Median | 30.0 | 26.6 | 11.7 | +18.3% |