SCLX · NASDAQ · Drug Manufacturers - General

Scilex (SCLX)

Commercializes non-opioid treatments for acute and chronic pain.

$5.36
After-hours close−0.00 (−0.06%)
At close$5.36(+3.88%)
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Scilex Holding CompanySCLX
Health Care

Markets ZTlido, ELYXYB, and GLOPERBA while developing additional non-opioid pain-treatment candidates. The commercial portfolio combines topical and oral therapies with licensed product rights.

Markets ZTlido, a prescription lidocaine topical system for pain associated with post-herpetic neuralgia, alongside ELYXYB, a ready-to-use celecoxib oral solution for acute migraine in adults, and GLOPERBA, an oral colchicine solution for adult gout-flare prophylaxis. Its commercial activities center on the United States, with ELYXYB rights also covering Canada.

Combines commercialization of approved pain treatments with development of SEMDEXA (SP-102), SP-103, and SP-104. The portfolio has expanded through exclusive licensing and acquired rights, and the operating model depends on acquiring, developing, and commercializing non-opioid products for acute and chronic pain.

Company facts

CEOHenry Ji, Ph.D.
ListedNov 11, 2022
ExchangeNASDAQ
HeadquartersPalo Alto, CA
CountryUnited States
Employees34
CIK0001820190
ISINUS80880W2052

Market cap$43.8M
EPS (ttm)−$64.88
P/E (ttm)−0.0795
ROE
P/B
P/S1.39
Dividend yieldDiv yield
Beta1.07vs XLV 0.30

No analyst consensus on record.

Next report
Dec 2, 26
estimated · in 71 days
EPS estimate
−$0.08
Revenue estimate
$17.0M
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Mar '25May '25Aug '25Nov '25Apr '26May '26Aug '26Dec '26
Reported−$0.02−$2.26−$4.62−$13.80−$4.60−$4.76−$16.65Pending
Estimate−$0.10−$4.20−$0.57−$13.80−$0.29−$0.21−$0.18−$0.08
Surprise+77.4%+46.2%−715.4%0.0%−1,471.9%−2,166.5%−9,083.2%

RevenueReportedEstimate

Mar '25May '25Aug '25Nov '25Apr '26May '26Aug '26Dec '26
Reported$14.9M$5.0M$9.9M$10.6M$4.8M$8.6M$7.6MPending
Estimate$17.8M$5.0M$26.3M$10.6M$12.1M$15.0M$16.0M$17.0M
Surprise−16.2%0.0%−62.3%0.0%−60.4%−42.6%−52.2%
Estimate−$0.08
ReportedDue Dec 2, 2026
Estimate$17.0M
ReportedDue Dec 2, 2026
View details

Current ratio7.10%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$14.4M$14.9M$5.0M$9.9M$10.6M$4.8M$8.6M$7.6M
Net income−$4.4M−$6.5M−$26.1M−$86.1M−$257.2M−$33.1M−$43.3M−$113.5M
Net margin0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$19.9M−$28.4M−$27.9M−$20.5M−$186.5M−$37.5M−$32.2M−$29.4M
YoY growthLoss narrowedLoss widenedLoss widenedLoss widenedLoss widenedLoss widenedLoss widenedLoss widened

Balance sheet, Jun 30, 2026Cash & short-term investments $581.0K · Total debt $95.6M · Total assets $253.6M · Shareholders' equity −$308.3M

Revenue
$7.6M
Operating income
−$29.4M
Net income
−$113.5M
View details

No dividends on record.

Institutions8.27%702.8K shares
71 holders · as of Jun 30, 2026
Insiders0.23%19.5K shares
7 holders · as of Dec 18, 2024
Strategic holders19.91%1.69M shares
2 holders · as of Jul 7, 2026
Other71.59%6.08M shares
remainder

8.49M company shares as of Sep 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesDate
SCLX Stock Acquisition JV LLCStrategic10 percent owner
11.28%958,263filed Jul 7, 2026
Oramed Pharmaceuticals Inc.Strategic
8.63%732,717filed May 8, 2025
Vanguard Capital Management LLCInstitution
3.55%301,292as of Jun 30, 2026
BlackRock, Inc.Institution
1.29%109,417as of Jun 30, 2026
Vanguard Fiduciary Trust CoInstitution
0.54%45,822as of Jun 30, 2026

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Apr 17, 2026Henry Jidirector, officer: Exec Chair, CEO and President−650,000$1.20
Apr 16, 2026Henry Jidirector, officer: Exec Chair, CEO and President+3,250,000$1.20
Apr 17, 2026Stephen Hoi Madirector, officer: CFO, COO and Secretary+650,000$1.20
Dec 30, 2025Scilex Holding Co10 percent owner−9,657,300$0.5394
Dec 29, 2025Scilex Holding Co10 percent owner−7,310,984$0.6555
View details

  • Teva (ADR)

    Generic topical lidocaine patches overlap with ZTlido and planned SP-103

  • AbbVie

    Acute migraine treatment overlaps through Ubrelvy

  • Pfizer

    Acute migraine treatment overlaps through Nurtec ODT and Zavzpret

CompareAfter-hours close

CompanyPriceChange
Scilex$5.36−0.06%$43.8M57.41.4−22.8%
Teva (ADR)$39.33−0.41%$46.66B66.814.12.7−0.8%
AbbVie$265.01−0.10%$467.37B74.517.57.3+10.2%
Pfizer$27.90−0.11%$158.10B36.710.02.5+2.6%
Median66.814.12.7+2.6%