TEM · NASDAQ · Medical - Healthcare Information Services

Tempus AI (TEM)

Links clinical testing, multimodal data, and AI applications across precision medicine.

$77.64
vs last close−0.39 (−0.50%)
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Tempus AI, Inc.TEM
Health Care

Sells oncology and hereditary diagnostics alongside data licensing, clinical-trial services, care-pathway software, and algorithmic applications. A shared multimodal data platform connects the testing and data businesses within one reportable segment, with operations based in Chicago and an extension into Japan through a joint venture.

Combines clinical diagnostics with a multimodal data platform for physicians and life-sciences customers. Diagnostics spans oncology and hereditary testing, while Data and applications includes Insights, Next, Trials, and Algos.

Laboratory testing generates molecular and clinical data that can be structured and de-identified for licensing, research, trial matching, care-gap identification, and algorithmic tools. This feedback loop connects the testing business with the software and data products.

Based in Chicago, the business operates as one reportable segment and extends its model into Japan through the SB Tempus joint venture. Execution depends on payer coverage and reimbursement, pharmaceutical and biotechnology research budgets, compliance with health-data and AI rules, and integration of acquired laboratories, datasets, software, and teams.

Company facts

CEOEric Lefkofsky
ListedJun 14, 2024
ExchangeNASDAQ
HeadquartersChicago, IL
CountryUnited States
Employees3,800
CIK0001717115
ISINUS88023B1035

Market cap$13.67B
EPS (ttm)−$1.44
P/E (ttm)−54.19
ROE-54.7%
P/B30.73
P/S9.55
Dividend yieldDiv yield
Beta2.55vs XLV 0.81

Price target$70.00−10.3%Average of 14 analysts
ConsensusBuy9 of 14 analysts
Ratings

Target rangeAs of Sep 21, 2026

Latest analyst notes

DateFirmActionPriorCurrent
Sep 21, 2026Goldman SachsInitiate
Rating: Target:
Rating: NeutralTarget: $75
Sep 11, 2026H.C. WainwrightReiterate
Rating: Target: $56
Rating: BuyTarget: $66
Sep 9, 2026UBSInitiate
Rating: Target:
Rating: NeutralTarget: $70
Sep 8, 2026Redburn PartnersTarget
Target:
Target: $67
Sep 2, 2026Raymond JamesTarget
Target:
Target: $80

Next report
Nov 3, 26
in 42 days
EPS estimate
−$0.07
Revenue estimate
$410.0M
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Feb '25May '25Aug '25Nov '25Feb '26May '26Jul '26Nov '26
Reported−$0.18−$0.24−$0.22−$0.11−$0.04−$0.13−$0.04Pending
Estimate−$0.15−$0.26−$0.23−$0.17−$0.04−$0.21−$0.14−$0.07
Surprise−20.0%+7.7%+4.3%+36.2%+8.8%+38.1%+72.0%

RevenueReportedEstimate

Feb '25May '25Aug '25Nov '25Feb '26May '26Jul '26Nov '26
Reported$200.7M$255.7M$314.6M$334.2M$367.2M$348.1M$382.5MPending
Estimate$248.8M$248.1M$297.7M$328.7M$362.6M$345.4M$379.7M$410.0M
Surprise−19.4%+3.1%+5.7%+1.7%+1.3%+0.8%+0.7%
Estimate−$0.07
ReportedDue Nov 3, 2026
Estimate$410.0M
ReportedDue Nov 3, 2026
View details

Debt to equity324.60%
Current ratio329.70%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$180.9M$200.7M$255.7M$314.6M$334.2M$367.2M$348.1M$382.5M
Net income−$75.8M−$13.0M−$68.0M−$42.8M−$80.0M−$54.2M−$125.9M$5.6M
Net margin0.0%0.0%0.0%0.0%0.0%0.0%0.0%1.5%

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$53.6M−$50.7M−$68.7M−$61.8M−$61.0M−$61.4M−$84.7M−$75.9M
YoY growthLoss widenedLoss narrowedLoss widenedLoss narrowedLoss widenedLoss widenedLoss widenedLoss widened

Balance sheet, Jun 30, 2026Cash & short-term investments $816.0M · Total debt $1.44B · Total assets $2.37B · Shareholders' equity $444.9M

Revenue
$382.5M
Operating income
−$75.9M
Net income
$5.6M
View details

No dividends on record.

Institutions61.78%111.48M shares
542 holders · as of Jun 30, 2026
Insiders32.53%58.69M shares
13 holders · as of Sep 18, 2026
Strategic holders17.28%31.17M shares
1 holder · as of Dec 12, 2024
Adds to111.59%

180.43M company shares as of Sep 22, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

These groups come from separate filings that can overlap, so they add to 111.59%; nothing is left for Other.

This company has 2 share classes; every stake here is a share of the whole company.

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesDate
Eric P. Lefkofsky1,2,3Insiderdirector, 10 percent owner, officer: CEO and Chairman
23.70%24.40M Afiled Feb 10, 2026
Red Sky Ventures LLC4Strategic10 percent owner
17.28%31.17M Afiled Dec 12, 2024
Bradley A. KeywellInsider10 percent owner
8.43%15.22M Afiled Jan 22, 2025
Ark Investment Management LLCInstitution
5.55%10.02M Aas of Jun 30, 2026
BlackRock, Inc.Institution
4.60%8.29M Aas of Jun 30, 2026
  1. Eric P. Lefkofsky reports a block also reported by Geode Capital Management, LLC; it is counted once, under Geode Capital Management, LLC.
  2. Eric P. Lefkofsky reports a block also reported by JPMorgan Chase & Co; it is counted once, under JPMorgan Chase & Co.
  3. The filed share classes (A, COMMON) could not be matched to the company's, so no percentage.
  4. Reported at 4.70% on Nov 13, 2025, under the 5% line, so no further filing is required.

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Sep 16, 2026Ryan Fukushimaofficer: CEO, Data−700$70.00
Sep 17, 2026Andrew Polovinofficer: EVP, Chief Legal Officer−2,951$75.00
Sep 17, 2026Ryan M. Bartolucciofficer: Chief Accounting Officer−7,062$75.00
Sep 17, 2026Eric P. Lefkofskydirector, 10 percent owner, officer: CEO and Chairman−200,000$80.57
Sep 1, 2026David R. Epsteindirector−250$65.55
View details

  • Caris Life Sciences

    Closest public peer in tumor profiling, liquid biopsy, and oncology data

  • Guardant Health

    Direct rival in oncology testing, MRD, and clinico-genomic data

  • Natera

    Major MRD rival with adjacent tumor profiling and hereditary testing

  • NeoGenomics

    Oncology lab network spanning diagnostics, MRD, trials, and data

  • IQVIA

    Scaled rival in life-sciences data, real-world evidence, and trials

  • GeneDx

    Direct hereditary-testing rival built on clinical exome and genome sequencing

  • Myriad Genetics

    Hereditary cancer and neuropsychiatric pharmacogenomics competitor

  • Labcorp

    Large lab rival in oncology, hereditary genetics, and MRD testing

Compare

CompanyPriceChange
Tempus AI$77.64−0.50%$13.67B9.5+21.6%
Caris Life Sciences$32.08+4.67%$8.66B85.6127.48.8+45.4%
Guardant Health$177.63+2.16%$23.33B19.7+44.3%
Natera$387.32+4.50%$53.08B19.6+37.7%
NeoGenomics$19.13−1.44%$498.7M68.80.7+11.2%
IQVIA$271.78+0.70%$44.42B33.520.02.6+8.7%
GeneDx$89.54−8.48%$2.92B137.16.4+11.4%
Myriad Genetics$3.93−2.00%$378.7M0.5−10.5%
Labcorp$310.04−3.41%$26.32B26.616.41.8+5.8%
Median33.568.84.5+11.3%